sentences:  It has been hypothesized that tension generated by amphitelic attachment (biorientation; the attachment of sister kinetochores to opposite spindle poles) pulls sister kinetochores apart, thus disrupting the interaction of Aurora B at the innermost portion of the centromere with microtubule binding sites on the fibrous corona of the outermost centromere.Specifically, the tension generated by biorientation pulls MCAK outside of the area of Aurora B localization.Thus, mitosis proceeds upon biorientation and dissociation of Aurora B from its substrates.