sentences:  At the death of the last legitimate male heir of the Gonzaga line in the Duchy of Mantua, Vincenzo II (1627), Charles inherited the title through an agreement.His son was married with Maria Gonzaga, daughter of former Duke Francesco IV.However, his succession spurred the enmity of Charles Emmanuel I of Savoy, who aimed at the Gonzaga lands of Montferrat, and, above all, of Spain and the Holy Roman Empire, which did not like a philo-French ruler in Mantua.