sentences:  Aurora B targets a number of proteins that localize to the cleavage furrow, including the type-III intermediate filament proteins vimentin, desmin, and glial fibrillary acidic protein (GFAP).In general, phosphorylation destabilizes intermediate filaments.Therefore, it has been proposed that phosphorylation of intermediate filaments at the cleavage furrow destabilizes the filaments in preparation for cytokinesis.