sentences:  There are several histone chaperones that are known to be involved in nucleosome assembly after replication.The FACT complex has been found to interact with DNA polymerase α-primase complex, and the subunits of the FACT complex interacted genetically with replication factors.The FACT complex is a heterodimer that does not hydrolyze ATP, but is able to facilitate "loosening" of histones in nucleosomes, but how the FACT complex is able to relieve the tight association of histones for DNA removal remains unanswered.