sentences:  Specialized proteins can recognize the marker and recruit histone deacetylases and methylases to re-establish the silencing.Nucleosome histone modifications could also be inherited during cell division, however, it is not clear whether it can work independently without the direction by DNA methylation.The two main tasks of transcription initiation are to provide RNA polymerase with an access to the promoter and to assemble general transcription factors with polymerase into a transcription initiation complex.