sentences:  There is some evidence to suggest that mediator in a yeast is involved in regulating RNA polymerase III (Pol III) transcripts of tRNAs In support of that evidence, an independent report showed specific association of mediator with Pol III in "Saccharomyces cerevisiae".Those authors also reported specific associations with RNA polymerase I and proteins involved in transcription elongation and RNA processing, supporting other evidence of mediator's involvement in elongation and processing.Mediator is involved in "looping" of chromatin, which brings distant regions of a chromosome into closer physical proximity.