sentences:  Cdc6 binds to the ORC on DNA in an ATP-dependent manner, which induces a change in the pattern of origin binding that requires Orc1 ATPase.Cdc6 requires ORC in order to associate with chromatin and is in turn required for the Cdt1-Mcm2-7 heptamer to bind to the chromatin.The ORC-Cdc6 complex forms a ring-shaped structure and is analogous to other ATP-dependent protein machines.