sentences:  This includes giving advice on recommendations on matters of both a 'routine' nature and also on any specific or special matters that Ministers may request.In formulating any advice and recommendations, the Committee must take into account the need for and impact of vaccines, the quality of vaccines and the strategies to ensure that their greatest benefit to the public health can be obtained from the most appropriate use of vaccines.JCVI members meet and report as one Committee usually three times a year.