sentences:  MSH6 was first identified in the budding yeast "S. cerevisiae" because of its homology to MSH2.The identification of the human GTBP gene and subsequent amino acid sequence availability showed that yeast MSH6 and human GTBP were more related to each other than any other MutS homolog, with a 26.6% amino acid identity.Thus, GTBP took on the name human MSH6, or hMSH6.