sentences:  While the eventual regulatory status of e-cigarettes in many countries remains uncertain, public health advocates view electronic cigarette as having a valid place within tobacco harm reduction strategy.In a first step towards the regulation of e-cigarettes, the MHRA granted Marketing Authorisations (licences) for the medicinal products e-Voke 10 mg and 15 mg Electronic Inhaler (PL 40317/0001-2) on 16 November 2015.Public health researchers in the UK estimated that 6,000 premature smoking-related deaths per year would be prevented for every million smokers who switched to e-cigarettes.