sentences:  His wife Sofia Angulo came from the high society of Popayan and married in 1877, whose union there were six children, namely Rafael, Enrique, Amalia, Nina, Sofia and Pedro Ignacio.In 1898 widower, and refuses to remarry.After finishing his studies at age 17, he and his siblings constituted an exports company called "Hermanos Reyes" (Spanish from the Reyes Brothers) that shipped Quina (Cinchona officinalis) from the isolated jungles of the Amazon rainforest and Putumayo River (Colombia) to Europe (Quina was used in the treatment of malaria).