sentences:  A difference between the ESV and CYV would be CYV's ability to independently replicate without on other viruses in insect cell culture.A non-AUG start codon in ORF5 has been shown in "Drosophila" and may regulate translation, which indicates its function in entomobirnavirus host in reactions.When ORF5 is expressed, it is thought to mediate ribosomal frameshifting.