sentences:  The translation of the large ORF transcript produces a 114-kDa polyprotein.The mature VP4 protein, viral protease, assists this process to increase the processing of the polyprotein to generate preVP2 capsid protein, VP3 viral ribonucleoprotein (RNP), and additional VP4 proteins.In addition VP3 proteins can associate with pre-VP2 as a structural protein and with VP1 to function as a transcriptional activator.