sentences:  Pharmacological methods, such as localized or regional pain-blocking injections and topical analgesic creams, are safe and effective.The ring block and dorsal penile nerve block (DPNB) are the most effective at reducing pain, and the ring block may be more effective than the DPNB.They are more effective than EMLA (eutectic mixture of local anesthetics) cream, which is more effective than a placebo.