sentences:  Penile cancer development can be detected in the carcinoma "in situ" (CIS) cancerous precursor stage and at the more advanced invasive squamous cell carcinoma stage.Childhood or adolescent circumcision is associated with a reduced risk of invasive squamous cell carcinoma in particular.There is an association between adult circumcision and an increased risk of invasive penile cancer; this is believed to be from men being circumcised as a treatment for penile cancer or a condition that is a precursor to cancer rather than a consequence of circumcision itself.