sentences:  Triosephosphate isomerase deficiency
  
  Triosephosphate isomerase deficiency is a rare autosomal recessive metabolic disorder which was initially described in 1965.It is a unique glycolytic enzymopathy that is characterized by chronic haemolytic anaemia, cardiomyopathy, susceptibility to infections, severe neurological dysfunction, and, in most cases, death in early childhood.