sentences:  The court dismissed the case, although Justice Breyer, Justice Stevens, and Justice Souter dissented from this decision.Breyer's dissenting opinion cited numerous cases in which scientific and mathematical principles had been held to be patent ineligible, including "O'Reilly v. Morse" and "Gottschalk v. Benson".Had the case been heard, and had Metabolite's patent been invalidated, the case would have had broad implications for biotechnology companies, which may have extended far beyond patentability of correlations of biomarkers to disease states.