sentences:  This result suggests that androgens may upregulate survivin, which contributes to the resistance to apoptosis observed in the tumour cells.Next, with the addition of flutamide (an antiandrogen) to the cells, survivin levels were observed to significantly decrease.The LNCaP cells were transduced separately with the different constructs of the survivin gene (mutant or wild-type) and subjected to flutamide treatment and assessed for the apoptosis level.