sentences:  Effect on nuclear factor kappa B 
  Certain poloxamers such as P85 have been shown not only to be able to transport target genes to target cells, but also to increase gene expression.Certain poloxamers, such as P85 and L61, have also been shown to stimulate transcription of NF kappaB genes, although the mechanism by which this is achieved is currently unknown, bar that P85 has been shown to induce phosphorylation of the inhibitory kappa.Potential degradation by sonication
  
  Wang et al.