sentences:  This insight is all the more remarkable because the model preceded the discovery of the structure of the DNA molecule as discussed above.It is also noteworthy that Von Neumann's design considers that mutations towards greater complexity need to occur in the (descriptions of) subsystems not involved in self-reproduction itself, as conceptualized by the additional automaton "D" he considered to perform all functions not directly involved in reproduction (see Figure above with Von Neumann's System of Self-Replication Automata with the ability to evolve.