sentences:  After examination, as both individual SNPs and at the haplotype level, it was discovered that the rs6715729 SNP showed a significant difference of the genotypic and allelic frequency between the two groups.At the haplotype level, they found two risk haplotypes for alcohol dependence that were formed from a combination of 3 SNPs, rs6715729, rs735668 and rs6741029, that also showed a significant difference between the two groups.Thus, these polymorphisms of the NK1R gene are indeed associated with the development of alcohol dependence.