sentences:  The priming of macrophages involves the enhancement of respiratory burst activity by IFN-γ and TNF-α.IFNγ induces both an increased affinity of the NADPH oxidase for NADPH in macrophages, as well as an increased rate of gene transcription and message expression for gp91phox protein.TNF-α acts as an autocrine stimulus by increasing the expression of both p47phox and p67phox transcripts.