sentences:  More recently, it has been proposed that MLA might be useful in reducing nicotine reward without precipitating symptoms of nicotine withdrawal.This suggestion was made on the basis of experiments in which [[intraperitoneal]] doses of ~4 mg/kg and 8 mg/kg of MLA significantly reduced nicotine self-administration in rats.Most recently, it has been suggested that MLA had potential in the treatment of cannabis dependence.