sentences:  If results are not adequate after 1 month of treatment, the dosage may be increased to 2 tablets per day, given in divided doses (1 tablet morning and evening) before meals.As a result of its good clinical and biological acceptability, rilmenidine may be administered to both elderly and diabetic hypertensive patients.In patients with kidney failure, no dosage adjustment is necessary in principle when the creatinine clearance is greater than 15 mL/min.