sentences:  The final era of the Casa da Índia began in 1822, during the reign of King John VI of Portugal, when a large number of its responsibilities were transferred to different ministries of the Portuguese Government.In 1833, the Casa da Índia was finally dissolved, by King Miguel I of Portugal, and its functions were absorbed by the "Alfândega de Lisboa" (Customs Agency of Lisbon).Although initially (c.1500) consolidated in one unit, the "Casa da Índia e da Guiné", it was separated again (c. 1506) into two distinct units, "Casa da Índia" and the "Casa da Mina e da Guiné" again.