sentences:  Development was stopped by manufacturer AstraZeneca, however, because of reports of liver enzyme derangements and liver failure.Dabigatran is an oral direct thrombin inhibitor.Dabigatran (Pradaxa) was found to be noninferior to Warfarin in prevention of ischemic stroke, as well as intracranial hemorrhage risk and overall mortality for non-valvular atrial fibrillation according to the RE-LY trial.