sentences:  Some of the factors being researched are EGF (which is known to enhance myelination), IGF-1, PDGF, and FGF 
  
  Toll-Like receptors are also involved in remyelination, most likely inhibiting remyelination and OPC differentiation.There are a variety of types of these receptors, but a majority of them tend to increase, especially in the chronic stages of demyelinating diseases, suggesting that they may be involved with remyelination failure.MicroRNA is not well understood but may play a minor or major role in remyelination.