sentences:  In 1987, the U.S. Government Accountability Office concluded that the food additive approval process had been followed properly for aspartame.The irregularities fueled a conspiracy theory, which the "Nancy Markle" email hoax circulated, along with claims – counter to the weight of medical evidence – that numerous health conditions (such as multiple sclerosis, systemic lupus, methanol toxicity, blindness, spasms, shooting pains, seizures, headaches, depression, anxiety, memory loss, birth defects, and death) are caused by the consumption of aspartame in normal doses.Aspartame is a methyl ester of the aspartic acid/phenylalanine dipeptide.