sentences:  These included unspecified composition of the "Corticella" diet and method of adding aspartame, leading to possible nutritional deficiencies; a contamination issue from unspecified aspartame storage conditions and handling; ignoring several industry standards — lack of animal randomization, use of the institute's randomly bred lines that remained pathogen carriers as opposed to readily available pathogen-free animals, use of full-life animals resulting in age variation at death and comparing those animals to younger controls, and both high-density housing and housing of different animal groups in different conditions; an unusually high incidence of confounding infections known to cause lymphoid neoplasmas and other lesions earlier and at greater rates in the test species; pooling of tumors (lymphomas and leukemias) from different tissue types despite standing research that induced tumors "can and should be differentiated from naturally occurring tumors" ; insufficient/incomplete/conflicting methodology and data collection/reporting in multiple areas; and the U.S. National Toxicology Program's finding that the ERF had misdiagnosed hyperplasias as malignancies.Finding comprehensive contradiction in the research literature of any reasonable danger, in combination with the ERF's design and implementation issues, Magnuson concluded the research did not constitute credible evidence for the carcinogenicity of aspartame.Another review criticized the ERF for relying on "science by press conference" with its release of results through the media before being published in a proper peer-reviewed journal, thus helping fuel the controversy and publicity about the study in the media.