Okay, let's tackle this math problem. We're starting with 164933 and subtracting 52812.

Step 1: We'll start by subtracting the digit 2 and the borrow 0 from 3 in column 1 and get 1.
1 is the first digit of our result.

Step 2: We'll start by subtracting the digit 1 and the borrow 0 from 3 in column 2 and get 2.
2 is the next digit of our result.

Step 3: We'll start by subtracting the digit 8 and the borrow 0 from 9 in column 3 and get 1.
1 is the next digit of our result.

Step 4: We'll start by subtracting the digit 2 and the borrow 0 from 4 in column 4 and get 2.
2 is the next digit of our result.

Step 5: We'll start by subtracting the digit 5 and the borrow 0 from 6 in column 5 and get 1.
1 is the next digit of our result.

Step 6: We'll start by subtracting the digit 0 and the borrow 0 from 1 in column 6 and get 1.
1 is the next digit of our result.

So, 164933 - 52812 = 112121.