Got it! So, we have 59373 and 8449, and we'll subtract the latter from the former.

Step 1: We'll start by subtracting the digit 9 and the borrow 0 from 3 in column 1 and get -6.
We add -6 to 10 and get 4 as the first digit of the result.

Step 2: We'll start by subtracting the digit 4 and the borrow 1 from 7 in column 2 and get 2.
2 is the next digit of our result.

Step 3: We'll start by subtracting the digit 4 and the borrow 0 from 3 in column 3 and get -1.
We add -1 to 10 and get 9 as the next digit of the result.

Step 4: We'll start by subtracting the digit 8 and the borrow 1 from 9 in column 4 and get 0.
0 is the next digit of our result.

Step 5: We'll start by subtracting the digit 0 and the borrow 0 from 5 in column 5 and get 5.
5 is the next digit of our result.

So, 59373 - 8449 = 50924.