We can solve this together! We're beginning with 573293 and removing 82878 from it.

Step 1: We'll start by subtracting the digit 8 and the borrow 0 from 3 in column 1 and get -5.
We add -5 to 10 and get 5 as the first digit of the result.

Step 2: We'll start by subtracting the digit 7 and the borrow 1 from 9 in column 2 and get 1.
1 is the next digit of our result.

Step 3: We'll start by subtracting the digit 8 and the borrow 0 from 2 in column 3 and get -6.
We add -6 to 10 and get 4 as the next digit of the result.

Step 4: We'll start by subtracting the digit 2 and the borrow 1 from 3 in column 4 and get 0.
0 is the next digit of our result.

Step 5: We'll start by subtracting the digit 8 and the borrow 0 from 7 in column 5 and get -1.
We add -1 to 10 and get 9 as the next digit of the result.

Step 6: We'll start by subtracting the digit 0 and the borrow 1 from 5 in column 6 and get 4.
4 is the next digit of our result.

So, 573293 - 82878 = 490415.