No problem, let's work through this together. We're starting with 413300 and are subtracting 37373 from it.

Step 1: We'll start by subtracting the digit 3 and the borrow 0 from 0 in column 1 and get -3.
We add -3 to 10 and get 7 as the first digit of the result.

Step 2: We'll start by subtracting the digit 7 and the borrow 1 from 0 in column 2 and get -8.
We add -8 to 10 and get 2 as the next digit of the result.

Step 3: We'll start by subtracting the digit 3 and the borrow 1 from 3 in column 3 and get -1.
We add -1 to 10 and get 9 as the next digit of the result.

Step 4: We'll start by subtracting the digit 7 and the borrow 1 from 3 in column 4 and get -5.
We add -5 to 10 and get 5 as the next digit of the result.

Step 5: We'll start by subtracting the digit 3 and the borrow 1 from 1 in column 5 and get -3.
We add -3 to 10 and get 7 as the next digit of the result.

Step 6: We'll start by subtracting the digit 0 and the borrow 1 from 4 in column 6 and get 3.
3 is the next digit of our result.

So, 413300 - 37373 = 375927.