Sure thing! We've got 788468 and 39408, and we're going to subtract the second number from the first.

Step 1: We'll start by subtracting the digit 8 and the borrow 0 from 8 in column 1 and get 0.
0 is the first digit of our result.

Step 2: We'll start by subtracting the digit 0 and the borrow 0 from 6 in column 2 and get 6.
6 is the next digit of our result.

Step 3: We'll start by subtracting the digit 4 and the borrow 0 from 4 in column 3 and get 0.
0 is the next digit of our result.

Step 4: We'll start by subtracting the digit 9 and the borrow 0 from 8 in column 4 and get -1.
We add -1 to 10 and get 9 as the next digit of the result.

Step 5: We'll start by subtracting the digit 3 and the borrow 1 from 8 in column 5 and get 4.
4 is the next digit of our result.

Step 6: We'll start by subtracting the digit 0 and the borrow 0 from 7 in column 6 and get 7.
7 is the next digit of our result.

So, 788468 - 39408 = 749060.