Let's dive into this subtraction. We'll start with 468700 and subtract 12379 from it.

Step 1: We'll start by subtracting the digit 9 and the borrow 0 from 0 in column 1 and get -9.
We add -9 to 10 and get 1 as the first digit of the result.

Step 2: We'll start by subtracting the digit 7 and the borrow 1 from 0 in column 2 and get -8.
We add -8 to 10 and get 2 as the next digit of the result.

Step 3: We'll start by subtracting the digit 3 and the borrow 1 from 7 in column 3 and get 3.
3 is the next digit of our result.

Step 4: We'll start by subtracting the digit 2 and the borrow 0 from 8 in column 4 and get 6.
6 is the next digit of our result.

Step 5: We'll start by subtracting the digit 1 and the borrow 0 from 6 in column 5 and get 5.
5 is the next digit of our result.

Step 6: We'll start by subtracting the digit 0 and the borrow 0 from 4 in column 6 and get 4.
4 is the next digit of our result.

So, 468700 - 12379 = 456321.