Alright, let's solve this problem step by step. We have 7523 and 2746, and we're subtracting the second number from the first.

Step 1: We'll start by subtracting the digit 6 and the borrow 0 from 3 in column 1 and get -3.
We add -3 to 10 and get 7 as the first digit of the result.

Step 2: We'll start by subtracting the digit 4 and the borrow 1 from 2 in column 2 and get -3.
We add -3 to 10 and get 7 as the next digit of the result.

Step 3: We'll start by subtracting the digit 7 and the borrow 1 from 5 in column 3 and get -3.
We add -3 to 10 and get 7 as the next digit of the result.

Step 4: We'll start by subtracting the digit 2 and the borrow 1 from 7 in column 4 and get 4.
4 is the next digit of our result.

So, 7523 - 2746 = 4777.