Let's dive into this subtraction. We'll start with 64597 and subtract 59901 from it.

Step 1: We'll start by subtracting the digit 1 and the borrow 0 from 7 in column 1 and get 6.
6 is the first digit of our result.

Step 2: We'll start by subtracting the digit 0 and the borrow 0 from 9 in column 2 and get 9.
9 is the next digit of our result.

Step 3: We'll start by subtracting the digit 9 and the borrow 0 from 5 in column 3 and get -4.
We add -4 to 10 and get 6 as the next digit of the result.

Step 4: We'll start by subtracting the digit 9 and the borrow 1 from 4 in column 4 and get -6.
We add -6 to 10 and get 4 as the next digit of the result.

Step 5: We'll start by subtracting the digit 5 and the borrow 1 from 6 in column 5 and get 0.
0 is the next digit of our result.

So, 64597 - 59901 = 4696.