Alright, let's solve this problem step by step. We have 80002 and 4527, and we're subtracting the second number from the first.

Step 1: We'll start by subtracting the digit 7 and the borrow 0 from 2 in column 1 and get -5.
We add -5 to 10 and get 5 as the first digit of the result.

Step 2: We'll start by subtracting the digit 2 and the borrow 1 from 0 in column 2 and get -3.
We add -3 to 10 and get 7 as the next digit of the result.

Step 3: We'll start by subtracting the digit 5 and the borrow 1 from 0 in column 3 and get -6.
We add -6 to 10 and get 4 as the next digit of the result.

Step 4: We'll start by subtracting the digit 4 and the borrow 1 from 0 in column 4 and get -5.
We add -5 to 10 and get 5 as the next digit of the result.

Step 5: We'll start by subtracting the digit 0 and the borrow 1 from 8 in column 5 and get 7.
7 is the next digit of our result.

So, 80002 - 4527 = 75475.