Alright, let's solve this problem step by step. We have 50367 and 16074, and we're subtracting the second number from the first.

Step 1: We'll start by subtracting the digit 4 and the borrow 0 from 7 in column 1 and get 3.
3 is the first digit of our result.

Step 2: We'll start by subtracting the digit 7 and the borrow 0 from 6 in column 2 and get -1.
We add -1 to 10 and get 9 as the next digit of the result.

Step 3: We'll start by subtracting the digit 0 and the borrow 1 from 3 in column 3 and get 2.
2 is the next digit of our result.

Step 4: We'll start by subtracting the digit 6 and the borrow 0 from 0 in column 4 and get -6.
We add -6 to 10 and get 4 as the next digit of the result.

Step 5: We'll start by subtracting the digit 1 and the borrow 1 from 5 in column 5 and get 3.
3 is the next digit of our result.

So, 50367 - 16074 = 34293.