Sure thing! We've got 49936 and 16100, and we're going to subtract the second number from the first.

Step 1: We'll start by subtracting the digit 0 and the borrow 0 from 6 in column 1 and get 6.
6 is the first digit of our result.

Step 2: We'll start by subtracting the digit 0 and the borrow 0 from 3 in column 2 and get 3.
3 is the next digit of our result.

Step 3: We'll start by subtracting the digit 1 and the borrow 0 from 9 in column 3 and get 8.
8 is the next digit of our result.

Step 4: We'll start by subtracting the digit 6 and the borrow 0 from 9 in column 4 and get 3.
3 is the next digit of our result.

Step 5: We'll start by subtracting the digit 1 and the borrow 0 from 4 in column 5 and get 3.
3 is the next digit of our result.

So, 49936 - 16100 = 33836.