Let's get this math done. We have 64003 and 48852, and we're going to subtract the second number from the first.

Step 1: We'll start by subtracting the digit 2 and the borrow 0 from 3 in column 1 and get 1.
1 is the first digit of our result.

Step 2: We'll start by subtracting the digit 5 and the borrow 0 from 0 in column 2 and get -5.
We add -5 to 10 and get 5 as the next digit of the result.

Step 3: We'll start by subtracting the digit 8 and the borrow 1 from 0 in column 3 and get -9.
We add -9 to 10 and get 1 as the next digit of the result.

Step 4: We'll start by subtracting the digit 8 and the borrow 1 from 4 in column 4 and get -5.
We add -5 to 10 and get 5 as the next digit of the result.

Step 5: We'll start by subtracting the digit 4 and the borrow 1 from 6 in column 5 and get 1.
1 is the next digit of our result.

So, 64003 - 48852 = 15151.