Got it! So, we have 245844 and 22417, and we'll subtract the latter from the former.

Step 1: We'll start by subtracting the digit 7 and the borrow 0 from 4 in column 1 and get -3.
We add -3 to 10 and get 7 as the first digit of the result.

Step 2: We'll start by subtracting the digit 1 and the borrow 1 from 4 in column 2 and get 2.
2 is the next digit of our result.

Step 3: We'll start by subtracting the digit 4 and the borrow 0 from 8 in column 3 and get 4.
4 is the next digit of our result.

Step 4: We'll start by subtracting the digit 2 and the borrow 0 from 5 in column 4 and get 3.
3 is the next digit of our result.

Step 5: We'll start by subtracting the digit 2 and the borrow 0 from 4 in column 5 and get 2.
2 is the next digit of our result.

Step 6: We'll start by subtracting the digit 0 and the borrow 0 from 2 in column 6 and get 2.
2 is the next digit of our result.

So, 245844 - 22417 = 223427.