Okay, let's tackle this math problem. We're starting with 993291 and subtracting 12845.

Step 1: We'll start by subtracting the digit 5 and the borrow 0 from 1 in column 1 and get -4.
We add -4 to 10 and get 6 as the first digit of the result.

Step 2: We'll start by subtracting the digit 4 and the borrow 1 from 9 in column 2 and get 4.
4 is the next digit of our result.

Step 3: We'll start by subtracting the digit 8 and the borrow 0 from 2 in column 3 and get -6.
We add -6 to 10 and get 4 as the next digit of the result.

Step 4: We'll start by subtracting the digit 2 and the borrow 1 from 3 in column 4 and get 0.
0 is the next digit of our result.

Step 5: We'll start by subtracting the digit 1 and the borrow 0 from 9 in column 5 and get 8.
8 is the next digit of our result.

Step 6: We'll start by subtracting the digit 0 and the borrow 0 from 9 in column 6 and get 9.
9 is the next digit of our result.

So, 993291 - 12845 = 980446.