We have numbers 2101 and 4121. Let's start adding them together.

Step 1: We'll start by adding the digits 1 & 1 in column 1 and get 2.

Step 2: We'll start by adding the digits 0 & 2 in column 2 and get 2.

Step 3: We'll start by adding the digits 1 & 1 in column 3 and get 2.

Step 4: We'll start by adding the digits 2 & 4 in column 4 and get 6.

So, 2101 + 4121 = 6222.

