Okay, let's tackle this math problem. We're starting with 99980 and subtracting 96224.

Step 1: We'll start by subtracting the digit 4 and the borrow 0 from 0 in column 1 and get -4.
We add -4 to 10 and get 6 as the first digit of the result.

Step 2: We'll start by subtracting the digit 2 and the borrow 1 from 8 in column 2 and get 5.
5 is the next digit of our result.

Step 3: We'll start by subtracting the digit 2 and the borrow 0 from 9 in column 3 and get 7.
7 is the next digit of our result.

Step 4: We'll start by subtracting the digit 6 and the borrow 0 from 9 in column 4 and get 3.
3 is the next digit of our result.

Step 5: We'll start by subtracting the digit 9 and the borrow 0 from 9 in column 5 and get 0.
0 is the next digit of our result.

So, 99980 - 96224 = 3756.