Alright, ready to do some subtraction? We're taking 74291 and subtracting 12162 from it.

Step 1: We'll start by subtracting the digit 2 and the borrow 0 from 1 in column 1 and get -1.
We add -1 to 10 and get 9 as the first digit of the result.

Step 2: We'll start by subtracting the digit 6 and the borrow 1 from 9 in column 2 and get 2.
2 is the next digit of our result.

Step 3: We'll start by subtracting the digit 1 and the borrow 0 from 2 in column 3 and get 1.
1 is the next digit of our result.

Step 4: We'll start by subtracting the digit 2 and the borrow 0 from 4 in column 4 and get 2.
2 is the next digit of our result.

Step 5: We'll start by subtracting the digit 1 and the borrow 0 from 7 in column 5 and get 6.
6 is the next digit of our result.

So, 74291 - 12162 = 62129.