Let's dive into this subtraction. We'll start with 411583 and subtract 99221 from it.

Step 1: We'll start by subtracting the digit 1 and the borrow 0 from 3 in column 1 and get 2.
2 is the first digit of our result.

Step 2: We'll start by subtracting the digit 2 and the borrow 0 from 8 in column 2 and get 6.
6 is the next digit of our result.

Step 3: We'll start by subtracting the digit 2 and the borrow 0 from 5 in column 3 and get 3.
3 is the next digit of our result.

Step 4: We'll start by subtracting the digit 9 and the borrow 0 from 1 in column 4 and get -8.
We add -8 to 10 and get 2 as the next digit of the result.

Step 5: We'll start by subtracting the digit 9 and the borrow 1 from 1 in column 5 and get -9.
We add -9 to 10 and get 1 as the next digit of the result.

Step 6: We'll start by subtracting the digit 0 and the borrow 1 from 4 in column 6 and get 3.
3 is the next digit of our result.

So, 411583 - 99221 = 312362.