Dros yr 11 mlynedd diwethaf mae rhaglen Sêr Cymru wedi addasu i gyd-fynd â newidiadau ym maes ymchwil, ac arweinwyr datblygu ac arloesi, sydd yn ei dro wedi ymateb i faterion economaidd ac iechyd megis canlyniadau ymadael â’rUE ac effeithiau pandemig COVID-19.  Mae’r rhaglen wedi cynhyrchu dros £252 miliwn mewn incwm ymchwil fel enillion drwy fuddsoddiad o £110 miliwn gan Lywodraeth Cymru, gan lwyddo i adeiladu capasiti a gallu ym maes ymchwil Cymru.
Over the past 11 years the Sêr Cymru programme has adapted to align with changing research, development and innovation drivers, which in turn have responded to economic and health issues such as the aftermath of leaving the EU and impacts of the Covid-19 pandemic. It has generated over £252 million in research income as a return for £110 million investment by Welsh Government, successfully building research capacity and capability in Wales.