Gofynnodd Llywodraeth Cymru i Iechyd Cyhoeddus Cymru a grŵp annibynnol o arbenigwyr ar HIV gynnal yr astudiaeth er mwyn darparu tystiolaeth o effeithiolrwydd PrEP i atal HIV.
The Welsh Government asked Public Health Wales and an independent HIV expert group to run the study to provide evidence for the acceptability and effectiveness of PrEP in HIV prevention.