Ym mis Tachwedd 2017, derbyniodd y Pwyllgor Deisebau ddeiseb am Orkambi® a chael gwybod bod tystiolaeth newydd gan Vertex am ei heffeithiolrwydd clinigol.  Yn hytrach na chyflwyno’r dystiolaeth newydd i NICE, a wnaeth y gwerthusiad gwreiddiol, dywedodd Vertex y byddent ei hanfon at AWMSG.  Llythyrais at Vertex y llynedd a’i annog i gyflawni’r ymrwymiad hwn.  Hyd yn hyn, ni chyflwynwyd dim tystiolaeth newydd i AWMSG.
In November 2017 the Petitions Committee received a petition about Orkambi® and was told that Vertex had new evidence of its clinical effectiveness. Instead of presenting the new evidence to NICE, who carried out the original appraisal, Vertex said that they would send it to AWMSG. I wrote to Vertex last year urging them to fulfil this commitment. To date no new evidence has been submitted to AWMSG.