Mae’r ffaith bod amrywiolyn Omicron wedi codi’i ben yn destun pryder mawr, ac mae cryn ansicrwydd am yr effaith y mae’n debygol o’i chael; mae gwybodaeth o Dde Affrica, ynghyd â’r ffaith ei fod yn lledaenu’n gyflym ledled y byd, yn awgrymu'n gryf bod ganddo fantais o ran ei drosglwyddadwyedd. Nid oes digon o wybodaeth ar hyn o bryd inni fedru barnu a oes ganddo’r potensial i ddianc rhag effaith brechlynnau, ac rydym yn parhau’n ansicr am y symptomatoleg a graddau'r difrifoldeb clinigol mewn unigolion heintiedig.
The identification of the Omicron variant is a matter of significant concern and there is considerable uncertainty as to its likely impact; intelligence from South Africa together with rapid global dissemination strongly suggest a transmissibility advantage. There is insufficient information at present to make a judgment about potential for vaccine escape and both the symptomatology and the degree of clinical severity in infected individuals remain uncertain.