Mae Llywodraeth Cymru yn un o aelodau sefydlu Cynghrair Mersi a’r Ddyfrdwy, sy'n sicrhau cydweithredu trawsffiniol er budd y ddau ranbarth. Mae'r Gynghrair wedi arwain at nifer o lwyddiannau dros y blynyddoedd, ond roedd gwaith rhwng partneriaid ar y ddwy ochr yn hanfodol yn ystod y pandemig.
The Welsh Government is a founder member of the Mersey Dee Alliance, which ensures cross-border co-operation to benefit both regions. The Alliance has yielded numerous successes over the years but work between partners on both sides of the border was crucial during the pandemic.