Un o heriau cyntaf y Fenter i gael ei rhedeg fel cystadleuaeth yng Nghymru oedd gan Fwrdd Iechyd Prifysgol Betsi Cadwaladr.  Roedd y Bwrdd Iechyd am wella gofal cleifion drwy helpu nyrsys a gofalwyr i leihau dyletswyddau gweinyddol, fel y gallent dreulio rhagor o amser gyda chleifion.
One of the first SBRI challenges run in Wales was by Betsi Cadwaladr University Health Board (UHB) which wanted to develop a solution to improve patient care by helping nurses and carers reduce administration duties so they could spend more time with patients.