Mae hon yn ganolfan o'r radd flaenaf. Cafodd ei hariannu yn llawn ag £20 miliwn gan Lywodraeth Cymru ac mae’n cael ei rheoli gan Brifysgol Sheffield. Mae’n  canolbwyntio ar sectorau gweithgynhyrchu uwch, gan gynnwys y sectorau awyrofod, modurol, niwclear a bwyd. Rhagwelir y gallai'r cyfleuster newydd ychwanegu gwerth ychwanegol gros o £4 biliwn at economi Cymru dros yr 20 mlynedd nesaf.
The state-of-the-art centre, which was fully funded with £20 million from Welsh Government and is managed by the University of Sheffield, focuses on advanced manufacturing sectors including aerospace, automotive, nuclear and food. It is predicted the new facility could increase GVA to the Welsh economy by as much as £4 billion over the next 20 years.