Yn 2016, derbyniodd Creo Medical £2m o fuddsoddiad gan Lywodraeth Cymru gyda chymorth Cyllid Cymru - sef Banc Datblygu Cymru erbyn hyn - i'w helpu i ddenu buddsoddiad o £20m a'i alluogodd i greu 22 o swyddi bras o'r ansawdd uchaf. Mae'r cwmni wedi cael cyngor  ar fuddsoddi hefyd gan Raglen Cyflymu Twf Busnes Cymru Llywodraeth Cymru, sy'n cael ei hariannu'n rhannol gan Gronfa Datblygu Rhanbarthol Ewrop, i gefnogi'r buddsoddiad.
In 2016 Creo Medical received a £2m investment from the Welsh Government supported Finance Wales – now the Development Bank of Wales which helped it to secure a £20m investment, facilitating the creation of 22 high quality, well paid jobs. In addition the company has received investment advice from the Welsh Government’s Business Wales  Accelerated Growth Programme,  part funded by European Regional Development fund,  to support this investment.