Daeth Gweithrediaeth GIG Cymru yn weithredol ar 1 Ebrill 2023. Roedd hwn yn ymrwymiad a gafodd ei wneud ynCymru Iachach, fel yr argymhellwyd gan yr Adolygiad Seneddol o Ddyfodol Hirdymor Iechyd a Gofal Cymdeithasol, gyda'r nod o gydgrynhoi gweithgarwch cenedlaethol a chreu dull gweithredu cyson ar gyfer cynllunio, pennu blaenoriaethau ar sail canlyniadau, rheoli perfformiad ac atebolrwydd. Cafodd yr ymrwymiad ei ailgadarnhau yn y Rhaglen Lywodraethu.
The NHS Wales Executive became operational on 1 April 2023. This was a commitment made inA Healthier Wales, as recommended by the Parliamentary Review of the Long-term Future of Health and Social Care, with the aim of consolidating national activity and bringing a consistent approach to planning, priority setting based on outcomes, performance management and accountability. It was reconfirmed in the Programme for Government.