Mae’r Gell Cyngor Technegol yn cael ei chadeirio ar y cyd gan Dr Orford a’r Dirprwy Gyfarwyddwr Technoleg a Digidol. Daw’r Aelodau o Lywodraeth Cymru, Iechyd Cyhoeddus Cymru, Prifysgol Caerdydd a Phrifysgol Abertawe. Mae’n cynnwys amryw o arbenigwyr o wahanol ddisgyblaethau gan gynnwys iechyd, diogelu iechyd, meddygaeth, epidemioleg, modelu, technoleg, gwyddor data, ystadegau, microbioleg, bioleg foleciwlaidd, imiwnoleg, genomeg, gwyddorau ffisegol ac ymchwil.
TAC is co-chaired by Dr Orford and the Deputy Director for Technology and Digital. Membership is drawn from Welsh Government, Public Health Wales, Cardiff University and Swansea University. A range of experts from different disciplines are included covering public health, health protection, medicine, epidemiology, modelling, technology, data science, statistics, microbiology, molecular biology, immunology, genomics, physical sciences and research.