Brazilian Controlled Drugs and Substances Act
The Brazilian Controlled Drugs and Substances Act (), officially Portaria nº 344/1998, is Brazil's federal drug control statute, issued by the Ministry of Health through its National Health Surveillance Agency (Anvisa). The act also serves as the implementing legislation for the Single Convention on Narcotic Drugs, the Convention on Psychotropic Substances, and the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances in the country.

The list was last updated in July 2023.

Terminology:

 Prescription notification - a standardized document intended for notifying Anvisa of the prescription of medications. Written by the doctor and retained by the drugstore
 Prescription - a written medication order that provides usage instructions for the patient.
 Special control prescription - a prescrition that is filled out in two copies, one that is retained by the drugstore, and another stays with the patient for usage guidance. It can be provided in a digital signed form.

Overview

Class A1 

 Acetylmethadol
 Alphacetylmethadol
 Alphameprodine
 Alphamethadol
 Alphaprodine
 Alfentanil
 Allylprodine
 Anileridine
 Bezitramide
 Benzethidine
 Benzylmorphine
 Benzoylmorphine ()
 Betaacetylmethadol
 Betameprodine
 Betamethadol
 Betaprodine
 Buprenorphine
 Butorphanol
 Clonitazene
 Codoxime
 Concentrated opium poppy straw
 Dextromoramide
 Diampromide
 Diethylthiambutene
 Diphenoxylate
 Difenoxin
 Dihydromorphine
 Dimepheptanol
 Dimenoxadol
 Dimethylthiambutene
 Dioxaphetyl butyrate
 Dipipanone
 Drotebanol
 Ethylmethylthiambutene
 Etonitazene
 Etoxeridine
 Phenadoxone
 Phenampromide
 Phenazocine
 Phenomorphan
 Phenoperidine
 Fentanyl
 Furethidine
 Hydrocodone
 Hydromorphinol
 Hydromorphone
 Hydroxypethidine
 Methadone intermediate
 Moramide intermediate
 Pethidine intermediate A
 Norpethidine (Pethidine intermediate B)
 Pethidinic acid (Pethidine intermediate C)
 Isomethadone
 Levophenacylmorphan
 Levomethorphan
 Levomoramide
 Levorphanol
 Methadone
 Metazocine
 Methyldesorphine
 Methyldihydromorphine
 Metopon
 Myrophine
 Morpheridine
 Morphine
 Morinamide
 Nicomorphine
 Noracymethadol
 Norlevorphanol
 Normethadone
 Normorphine
 Norpipanone
 Codeine-N-oxide
 Morphine-N-oxide
 Opium
 Oripavine
 Oxycodone
 Oxymorphone
 Pethidine
 Piminodine
 Piritramide
 Proheptazine
 Properidine
 Racemethorphan
 Racemoramide
 Racemorphan
 Remifentanil
 Sufentanil
 Tapentadol
 Thebacon
 Thebaine
 Tilidine
 Trimeperidine

Class A2 

 Acetyldihydrocodeine
 Codeine
 Dextropropoxyphene
 Dihydrocodeine
 Ethylmorphine (Dionine)
 Pholcodine
 Nalbufina
 Nalorphine
 Nicocodine
 Nicodicodine
 Norcodeine
 Propiram
 Tramadol

Class A3 

 Amphetamine
 Atomoxetine
 Cathine
 Chlorphentermine
 Dexamphetamine
 Dronabinol - Synthetic form with no other cannabinoid.
 Phenmetrazine
 Phencyclidine
 Phenethylline
 Levamphetamine
 Levomethamphetamine
 Lisdexamfetamine
 Methylphenidate
 Methylsynephrine
 Thamphetamine
 Cannabis sativa derivates containing up to 30mg/mL THC and 30mg/mL CBD

Class B1 

 Allobarbital
 Alprazolam
 Amineptine
 Amobarbital
 Aprobarbital
 Armodafinil
 Barbexaclone
 Barbital
 Bromazepam
 Bromazolam
 Brotizolam
 Butabarbital
 Butalbital
 Camazepam
 Ketamine
 Ketazolam
 Cyclobarbital
 Clobazam
 Clonazepam
 Clonazolam
 Chlorazepam (CAS: , , )
 Clorazepate
 Chlordiazepoxide
 Ethyl chloride
 Methylene chloride/dichloromethane
 Clotiazepam
 Cloxazolam
 Delorazepam
 Diazepam
 Diclazepam
 Esketamine
 Estazolam
 Eszopiclone
 Ethchlorvynol
 Ethylamphetamine (N-Ethylamphetamine)
 Ethinamate
 Etizolam
 Phenazepam
 Phenobarbital
 Flualprazolam
 Flubromazolam
 Fludiazepam
 Flunitrazepam
 Flurazepam
 GBL
 GHB
 Glutethimide
 Halazepam
 Haloxazolam
 Lefetamine
 Ethyl loflazepate
 Loprazolam
 Lorazepam
 Lormetazepam
 Medazepam
 Meprobamate
 Mesocarb
 Methylphenobarbital (prominal)
 Methyprylon
 Midazolam
 Modafinil
 Nimetazepam
 Nitrazepam
 Fencamfamin
 Nordazepam
 Oxazepam
 Oxazolam
 Pemoline
 Pentazocine
 Pentobarbital
 Perampanel
 Pinazepam
 Pipradrol
 Pyrovalerone
 Prazepam
 Prolintane
 Propylhexedrine
 Secbutabarbital
 Secobarbital
 Temazepam
 Tetrazepam
 Thiamylal
 Thiopental
 Triazolam
 Trichlorethylene
 Trihexyphenidyl
 Vinylbital
 Zaleplon
 Zolpidem
 Zopiclone
 Cannabis derivates containing up to 0,2% THC

Class B2 

 Aminorex
 Amfepramone
 Fenproporex
 Phendimetrazine
 Phentermine
 Mazindol
 Mefenorex
 Sibutramine

Class C1 

 Acepromazine
 Valproic acid
 Agomelatine
 Amantadine
 Amisulpride
 Amitriptyline
 Amoxapine
 Aripiprazole
 Asenapine
 Azacyclonol
 Beclamide
 Benactyzine
 Benfluorex
 Benzydamine
 Benzoctamine
 Benzquinamide
 Biperiden
 Brexpiprazole
 Brivaracetam
 Bupropion
 Buspirone
 Butaperazine
 Butriptyline
 Cannabidiol - Synthetic form with no other cannabinoid.
 Captodiame
 Carbamazepine
 Caroxazone
 Celecoxib
 Cyclarbamate
 Cyclexedrine (CAS: , )
 Cyclopentolate
 Cisapride
 Citalopram
 Clomacran
 Clomethiazole
 Clomipramine
 Chloralodol
 Chlorpromazine
 Chlorprothixene
 Clotiapine
 Clozapine
 Dapoxetine
 Desflurane
 Desipramine
 Desvenlafaxine
 Deutetrabenazine
 Dexetimide
 Dexmedetomidine
 Dibenzepine
 Dimetacrine
 Disopyramide
 Disulfiram
 Divalproex sodium
 Dixyrazine
 Donepezil
 Doxepin
 Droperidol
 Duloxetine
 Ectylurea (See Acylurea) (CAS: , )
 Emylcamate
 Enflurane
 Entacapone
 Escitalopram
 Etomidate
 Etoricoxib
 Ethosuximide
 Levophacetoperane
 Phenprobamate
 Phenaglycodol
 Phenelzine
 Pheniprazine
 Phenytoin
 Fluphenazine
 Flumazenil
 Fluoxetine
 Flupentixol
 Fluvoxamine
 Gabapentin
 Galantamine
 Haloperidol
 Halothane
 Chloral hydrate
 Etodroxizine (Hydrochlorbenzethylamine)
 Hydroxydione
 Homofenazine
 Imiclopazine 
 Imipramine
 Imipraminoxide
 Iproclozide
 Isocarboxazid
 Isoflurane
 Cenestil (Isopropyl-crotonyl-urea) (CAS: , ) 
 Lacosamide
 Lamotrigine
 Leflunomide
 Levetiracetam
 Levomepromazine
 Levomilnacipran
 Lisuride
 Lithium
 Loperamide
 Loxapine
 Lumiracoxib
 Lurasidone
 Mavacamten
 Maprotiline
 Meclofenoxate
 Mephenoxalone
 Mefexamide
 Memantine
 Mepazine
 Mesoridazine
 Methylnaltrexone
 Methylpentynol
 Methysergide
 Metixene
 Methopromazine (CAS: , )
 Methoxyflurane
 Mianserin
 Milnacipran
 Miltefosine
 Minaprine
 Mirtazapine
 Misoprostol - Hospital authorization only.
 Moclobemide
 Molnupiravir
 Moperone
 Naloxone
 Naltrexone
 Nefazodone
 Nialamide
 Isobutyl nitrite
 Nomifensine
 Nortriptyline
 Noxiptiline
 Olanzapine
 Opipramol
 Oxcarbazepine
 Oxybuprocaine
 Hydroxyphenamate
 Oxypertine
 Paliperidone
 Parecoxib
 Paroxetine
 Penfluridol
 Perphenazine
 Pergolide
 Pericyazine
 Pimozide
 Pipamperone
 Pipotiazine
 Pramipexole
 Pregabalin
 Primidone
 Prochlorperazine
 Promazine
 Propanidid
 Propiomazine
 Propofol
 Prothipendyl
 Protriptyline
 Proparacaine
 Quetiapine
 Ramelteon
 Rasagiline
 Reboxetine
 Ribavirin
 Rimonabant
 Risperidone
 Rivastigmine
 Rofecoxib
 Ropinirole
 Rotigotine
 Rufinamide
 Selegiline
 Sertraline
 Sevoflurane
 Sulpiride
 Sultopride
 Tacrine
 Teriflunomide
 Tetrabenazine
 Tetracaine
 Tiagabine
 Tianeptine
 Tiapride
 Thioproperazine
 Thioridazine
 Thiothixene
 Tolcapone
 Topiramate
 Tranylcypromine
 Trazodone
 Triclofos
 Trifluoperazine
 Trifluperidol
 Trimipramine
 Troglitazone
 Valdecoxib
 Sodium valproate
 Venlafaxine
 Veralipride
 Vigabatrin
 Vilazodone
 Vortioxetine
 Ziprasidone
 Zotepine
 Zuclopenthixol

Class C2 

 Acitretin
 Adapalene
 Bexarotene
 Isotretinoin
 Tretinoin

Class C3 

 Thalidomide
 Lenalidomide
 Pomalidomide

Class C4 
List revoked in September 2016.

Class C5 

 Androstanolone
 Bolasterone
 Boldenone
 Chlorodehydromethyltestosterone
 Clostebol
 Dehydrochlormethyltestosterone
 Drostanolone
 Stanolone
 Stanozolol
 Ethylestrenol
 Fluoxymesterone
 Formebolone
 Gestrinone
 Mesterolone
 Methandienone
 Methandranone 
 Methandriol
 Methenolone
 Methyltestosterone
 Mibolerone
 Nandrolone
 Norethandrolone
 Oxandrolone
 Oxymesterone
 Oxymetholone
 Prasterone (dehydroepiandrosterone - DHEA)
 Somatropin (Human Growth Hormone)
 Testosterone
 Trenbolone

Class D

Class D1 

 1-Boc-4-AP (CAS: , )
 1-phenyl-2-propanone
 3,4-MDP-2-P methyl glycidic acid (PMK glycidic acid)
 3,4-MDP-2-P methyl glycidate (PMK glycidate)
 3,4-Methylenedioxyphenyl-2-propanone
 4-AP (N-Phenyl-4-piperidinamine) 
 Anthranilic acid
 Phenylacetic acid
 Lysergic acid
 N-Acetylanthranilic acid
 Alpha-phenylacetoacetonitrile (APAAN) (CAS: , )
 Alpha-phenylacetoacetamide (APAA) (CAS: , )
 4-ANPP
 Dihydroergometrine
 Dihydroergotamine
 Ephedrine
 Ergometrine
 Ergotamine
 Etafedrine
 Helional
 Isosafrole
 Methyl alpha-acetylphenylacetate (MAPA) - (CAS: , )
 Norfentanyl
 Sassafras oil
 Long pepper oil
 Piperidine
 Piperonal
 Pseudoephedrine
 N-phenethyl-4-piperidinone (NPP)
 Safrole

Class D2 

 Acetone
 Hydrochloric acid
 Sulfuric acid
 Acetic anhydride
 Ethyl chloride
 Methylene Chloride
 Chloroform
 Ethyl Ether
 Methyl ethyl ketone
 Potassium permanganate
 Sodium sulphate
 Toluene
 Trichlorethylene

Class E 

 Cannabis sativa - except for registed products under allowed dosage mentioned in Class A3.
 Claviceps paspali (Ergot)
 Datura suaveolens
 Erythroxylum coca
 Lophophora williamsii (Coto Peyote)
 Papaver somniferum
 Prestonia amazonica
 Salvia divinorum

Class F

Class F1 

 2-Methyl-AP-237 (methyl analogue of bucinnazine)
 3-Methylfentanyl
 3-Methylthiofentanyl
 4-Fluoroisobutyrfentanyl
 Acetyl-alpha-methylfentanyl
 Acetylfentanyl
 Acetorphine
 Acryloylfentanyl
 AH-7921
 Alpha-methylfentanyl
 Alpha-methylthiofentanyl
 Beta-hydroxy-3-methylfentanyl
 Beta-hydroxyfentanyl
 Brorphine
 Butyrfentanyl
 Carfentanil
 Ketobemidone
 Cyclopropylfentanyl
 Cocaine
 Crotonylfentanyl
 Desomorphine
 Dihydroetorphine
 Ecgonine
 Etazene (Etodesnitazene)
 Etonitazepyne
 Etorphine
 Furanylfentanyl
 Heroin
 Isotonitazene
 MDPV
 Metonitazene
 Methoxyacetylfentanyl
 MPPP
 MT-45
 Ocfentanil
 Orthofluorofentanyl
 Parafluorobutyrfentanyl
 Parafluorofentanyl
 PEPAP
 Protonitazene
 Tetrahydrofuranylfentanyl
 Thiofentanyl
 U-47700
 Valerylfentanyl

Class F2 

 LSD
 1B-LSD
 1cP-LSD
 1P-LSD
 2C-B
 2C-C
 2C-D
 2C-E
 2C-F
 2C-I
 2C-T-2
 2C-T-7
 2-MeO-Diphenidine
 3-Fluorophenmetrazine
 3-MeO-PCP
 3-MMC
 4-AcO-DMT
 4-Bromomethcathinone
 4-Chloro-alpha-PVP
 4-Chloromethcathinone (4-CMC)
 4-Fluoroamphetamine (4-FA)
 4-Fluoromethcathinone
 4F-MDMB-BINACA
 4-HO-MIPT
 4-MEAPP
 4-MEC
 4-Methylaminorex
 4-MTA
 4,4'-DMAR
 5-APB
 5-APDB
 5C-MDA-19 (BZO-POXIZID, CAS: , )
 5-EAPB
 5F-AB-FUPPYCA
 5F-ADB
 5F-AKB48
 5F-AMB-PINACA
 5F-MDA-19 (5F-BZO-POXIZID, )
 5F-MDMB-PICA
 5F-PB-22
 5-IAI
 5-MAPDB
 5-MeO-AMT
 5-MeO-DALT
 5-MeO-DIPT
 5-MeO-DMT
 5-MeO-MIPT
 25B-NBOH
 25B-NBOMe
 25C-NBF
 25C-NBOH
 25C-NBOMe
 25D-NBOMe
 25E-NBOH
 25E-NBOMe
 25H-NBOH
 25H-NBOMe
 25I-NBF
 25I-NBOH
 25I-NBOMe
 25N-NBOMe
 25P-NBOMe
 25T2-NBOMe
 25T4-NBOMe
 25T7-NBOMe
 30C-NBOMe
 AB-CHMINACA
 AB-FUBINACA
 AB-PINACA
 ADB-BUTINACA ()
 ADB-CHMINACA
 ADB-FUBIATA
 ADB-FUBINACA
 ALD-52
 Alpha-EAPP
 Alpha-PHP
 alpha-PiHP
 Alpha-PVP
 AKB48
 AM-2201
 AMT
 Benzphetamine
 Bk-DMBDB
 Brolamphetamine
 BZP
 Cathinone
 CH-PIATA ()
 Clobenzorex
 CUMYL-4CN-BINACA
 CUMYL-PEGACLONE
 DET
 Diphenidine
 Dihydro-LSD (ChemSpider ID: 67024742) (8β)-N,N-Diethyl-6-methyl-9,10-didehydro-2,3-dihydroergoline-8-carboxamide
 Dimethylone
 DMA
 DMAA
 DMBA
 DMHP
 DMT
 DOC
 DOET
 DOI
 EAM-2201
 Ergine
 Eticyclidine
 Ethylphenidate
 Ethylone
 Etryptamine
 Eutylone
 FUB-AMB
 Isopropylbenzylamine
 JWH-018
 JWH-071
 JWH-072
 JWH-073
 JWH-081
 JWH-098
 JWH-122
 JWH-210
 JWH-250
 JWH-251
 JWH-252
 JWH-253
 MAM-2201
 MAM-2201 N-(4-hydroxypentyl) (CAS: , , )
 MAM-2201 N-(5-chloropentyl) (CAS: , , )
 MDMB-4en-PINACA
 MDMB-5Br-INACA
 mCPP
 MDA-19 (BZO-HEXOXIZID)
 MDAI
 MDE
 MDMA
 Mecloqualone
 Mephedrone
 Mescaline
 Methallylescaline
 Methanphetamine
 Methaqualone
 Methcathinone
 Methylone
 Methiopropamine
 MMDA
 MXE
 N-acetyl-3,4-MDMC (CAS: , )
 N-Ethylcathinone
 N-Ethylhexedrone (hexen)
 N-Ethylpentylone
 Parahexyl
 Pentedrone
 Pentylone
 PMA
 PMMA
 Psilocybin
 Psilocin
 RH-34
 Rolicyclidine (PCPy)
 Salvinorin A
 DOM (STP)
 Tenamfetamine
 Tenocyclidine
 THC - except for registed products under allowed dosage mentioned in Class A3.
 TH-PVP
 TMA
 TFMPP
 UR-144
 XLR-11
 Zipeprol

Class F3 
 Phenylpropanolamine (PPA) or norephedrine

Class F4 

 Dexfenfluramine
 Dinitrophenol
 Strychnine
 Etretinate
 Fenfluramine
 Lindane
 Terfenadine

References

Brazilian legislation
Drug control law
Drug policy of Brazil