2016 Italian Open – Women's singles
Serena Williams defeated Madison Keys in the final, 7–6(7–5), 6–3 to win the women's singles tennis title at the 2016 Italian Open. This was Williams's second title in Rome won without dropping a set, and her fourth Italian Open title overall.

Maria Sharapova was the reigning champion, but could not defend her title because of her provisional suspension after failing a drug test at the Australian Open.

Seeds
The top eight seeds received a bye into the second round.

Draw

Finals

Top half

Section 1

Section 2

Bottom half

Section 3

Section 4

Qualifying

Seeds

Qualifiers

Draw

First qualifier

Second qualifier

Third qualifier

Fourth qualifier

Fifth qualifier

Sixth qualifier

Seventh qualifier

Eighth qualifier

References

External links
Main draw
Qualifying draw

2016 WTA Tour
Women's Singles