Jesse Brown (disambiguation)
Jesse Brown (1944–2002) was the United States Secretary of Veterans Affairs under President Bill Clinton from 1993 to 1997.

Jesse Brown may also refer to:
Jesse L. Brown (1926–1950), American naval aviator
Jesse Brown (American football) (1902–1987), American football player
Jesse Brown (baseball) (1914–1980), American Negro leagues baseball player
Jesse Brown (journalist), Canadian journalist