Coffie is a surname and occasional given name. Notable people with this name include:

 Boyd Coffie (1937–2006), American baseball player
 Calton Coffie (1954–2023), Jamaican vocalist
 Eddie Coffie (1959–2015), Ghanaian actor
 Florence Oboshie Sai-Coffie (born 1953), Ghanaian politician and media executive
 Francis Coffie (born 1989), Ghanaian footballer
 Ivanon Coffie (born 1977), Dutch baseball player from Curaçao
 Naygel Coffie (born 1996), Bonaire footballer 
 Raymonde Coffie (born 1965), Ivorian politician
 Michael Coffie Boampong (1962–2018), Ghanaian accountant and politician
 Sunday Mbang (Sunday Coffie Mbang) (1936–2023), Nigerian Methodist prelate

See also
 Coffee (surname)
 Coffey (surname)
 Cofie, a surname