Campanile is an Italian surname. Notable people with the surname include:

 Achille Campanile (1899–1977), Italian writer, playwright, journalist and television critic
 Anthony Campanile (born 1982), American football coach
 Giovanni Agostino Campanile (died 1594), Roman Catholic prelate, Bishop of Minori (1567-1594)
 Pasquale Festa Campanile (1927–1986), Italian screenwriter, film director and novelist
 Raffaele Festa Campanile (born 1961), Italian television author, screenwriter, film director and music producer

Italian-language surnames