Susan Powell may refer to:

Susan Powell (Miss America) (born 1959), American actress, singer, and television personality
Susan Powell (weather forecaster) (born 1976/75), British weather reporter for the BBC
Susan Powell (cyclist) (born 1967), Australian Paralympic cyclist
Susan Marie Powell (born 1981), American woman disappearing in 2009
Sue Powell, member of the band Dave & Sugar (active 1975–1982)

See also
Sue Powell-Reed (active since 1980), Welsh radio & television broadcaster
Susan Noel-Powell (1912–1991), English squash and tennis player
Sue Johanson (née Powell; 1930–2023), Canadian sex educator.