Karaisalı is a municipality and district of Adana Province, Turkey. Its area is 1,165 km2, and its population is 22,042 (2022).

The area contains the reservoirs of Çatalan and Nergizlik. There is a wrestling tournament in late-April to early-May at Salbaş and a countryside festival in the last week of August at Kızıldağ.

History
In Greek and Roman times there was a town here named Midelle. Throughout history, the town was controlled by several kingdoms, such as the Seljuk Turks and Armenian Kingdom of Cilicia. Following the arrival of the Turks in the area the name was changed to Çeceli and inhabited by the Yüreğir and Menemencioğulları and  Ramazanoğulları tribes. 

Between 1481 and 1496 the town was controlled by the Mamluk Sultanate and once it was defeated by the Ottoman sultan Selim I, he left the control of the town to the Ramazanoğulları dynasty as a vassal state. The current name Karaisalı was later given in memory of a Ramazanoğulları lord. Right before his death in 1520 however, Selim I decided to formally annex the town and the surrounding region into the Ottoman Empire.

The town was not occupied by the Allies during the Turkish War of Independence in the early 1920s and became a centre of Turkish resistance against the Allies for the Çukurova area.

Composition
There are 62 neighbourhoods in Karaisalı District:

 Akçalı
 Aktaş
 Altınova
 Aşağıbelemedik
 Aşağıyörükler
 Ayakkıf
 Barakdağı
 Başkıf
 Bekirli
 Beydemir
 Bolacalı
 Boztahta
 Bucak
 Çakallı
 Çatalan
 Çeceli
 Çevlik
 Çocuklar
 Çorlu
 Çukur
 Demirçit
 Döşekevi
 Durak
 Eğlence
 Emelcik
 Etekli
 Fettahlı
 Filikli
 Gildirli
 Gökhasanlı
 Gülüşlü
 Güvenç
 Hacılı
 Hacımusalı
 Kaledağı
 Kapıkaya
 Karahasanlı
 Karakılıç
 Karakuyu
 Karapınar
 Kıralan
 Kırıklı
 Kocaveliler
 Körüklü
 Kuşcusofulu
 Kuyucu
 Kuzgun
 Maraşlı
 Murtçukuru
 Nergizlik
 Nuhlu
 Ömerli
 Sadıkali
 Sarımehmetli
 Saypınar
 Selampınar
 Tatık
 Topaktaş
 Topkaralı
 Torunsolaklı
 Tümenli
 Yazıbaşı

Places of interest
The Roman built Milvan Castle in the village of Karakılıç.
The silk road caravanserai Kesiri Han in the village of Altınova.
Another Roman castle Keçi Kalesi 40 km north-east of Karaisalı in the village of Etekli. has commanding views from its hill-top position.
The wooded hillside picnic areas of Yerköprü and Kızıldağ in particular Kapıkaya Canyon.
The attractive remote village of Kalayçılar. 7 km from the village of Hacılı on a dirt road.
Turkey's highest bridge, the  long and  high German built railway viaduct Varda Bridge in the village of Hacıkırı (Kıralan).
The Fish restaurant in Demirçit or otherwise known as Bolagat.

Notable people
Long-term mayor of Adana, Aytaç Durak is from Karaisalı and during his term the district was included in the Metropolitan Municipality of Adana.

References

 
Metropolitan district municipalities in Turkey
Districts of Adana Province
Populated places in Adana Province