PICS may refer to:
 Passive Inspection CubeSat, two nanosatellites launched in 2021
 Platform for Internet Content Selection, a content rating specification for websites
 Pacific Islands Central School/Pohnpei Island Central School, now Bailey Olter High School
 Post-intensive care syndrome
 Private investment capital subscription
 Protocol implementation conformance statement
 Punjab Institute of Computer Science
 Purdue Improved Crop Storage bags
 Phase Imaging with Computational Specificity

Pics or pics, may refer to:
 Slang abbreviation of pictures
 .pics, a generic top-level domain name administered by Cayman Islands-based company Uniregistry

See also
PIC (disambiguation)