Chileshe is a Zambian name. Notable people with this sname include:

 Chileshe Kapwepwe, Zambian politician
 Jack Chileshe (born 1983), Zambian football player
 Lwamba Chileshe (born 1999), Zambian-born New Zealand squash player
 Rhoda Chileshe (born 1998), Zambian football player
 Temwa Chileshe (born 2000), New Zealand squash player
 Vincent Chileshe, Zambian football player