In enzymology, an aldose 1-epimerase () is an enzyme that catalyzes the chemical reaction

alpha-D-glucose  beta-D-glucose

Hence, this enzyme has one substrate, alpha-D-glucose, and one product, beta-D-glucose.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives.  The systematic name of this enzyme class is aldose 1-epimerase. Other names in common use include mutarotase, and aldose mutarotase.  This enzyme participates in glycolysis and  gluconeogenesis.

Structural studies

As of late 2007, 23 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , , , , , , , , , , , , , , , and .

References

 
 
 
 

EC 5.1.3
Enzymes of known structure