Control Measures 
*
Proprietary Ind: Y
*
Contractor Summary 
*
*
Item Description Information 
*
Item Manager: S9M
Item Name: HOMATROPINE HYDROBROMIDE OPTHALMIC SOLUTION, USP
Type/Grade/Class: MEDICAL STRENGTH=5%
Unit of Issue: BT
*
Ingredients 
*
-----------------------------
*
Health Hazards Data 
*
Effects of Exposure: ACUTE: INHALATION: MAY BE IRRITATING TO MUCOUS MEMBRANES
  AND RESPIRATORY TRACT. SKIN CONTACT:PRODUCT CONFORMS TO FDA REGULATIONS AND
  GUIDELINES FOR AN OPHTHALMIC FORMULATION AND THUS IS NOT EXPECTED  TO PRODUCE
  DERMAL IRRITATION. EYE CONTACT: PRODUCT CONFORMS TO FDA REGULATIONS AND
  GUIDELINES FOR AN OPHTHALMIC FORMULATION THAT HAS BEEN DEMONSTRATED TO BE
  SAFE FOR USE IN THE EYE. MINIMAL OCULAR IR RITATION MAY OCCUR FOLLOWING AN
  EXCESSIVE EXPOSURE BEYOND THERAPEUTIC LEVELS SUCH AS IN PRODUCT ABUSE OR
  INDUSTRIAL ACCIDENT. SYSTEMIC EFFECTS IS POSSIBLE WITH EXCESSIVE TOPICAL
  OCULAR EXPOSURE. (CONT D. SEE "ECOLOGIAL")
Explanation Of Carcinogenicity: NOT DETERMINED
Signs And Symptions Of Overexposure: EYE, SKIN, INHALATION: RESPIRATORY TRACT
  IRRITATION, BLURRED VISION, DRY MOUTH, NOSE AND THROAT, INCREASED INTRAOCULAR
  PRESSURE, TRANSIENT BRADYCARDIA FOLLOWED BY TACHYCARDIA WITH PALPITATIONS AND
  ARR YTHMIAS. POSSIBLE ALLERGIC REACTION TO DUST IF INHALED.
Medical Cond Aggravated By Exposure: NOT PROVIDED BY MFR
First Aid: INHALATION:MOVE TO FRESH AIR. IF NOT BREATHING, PERFORM ARTIFICIAL
  RESUSCITATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. OBTAIN MEDICAL
  ATTENTION. SKIN: IN EVENT OF ADVERSE EFFECTS, OBTAINMEDICAL A TTENTION.
  ADVERSE EFFECTS, OBTAIN MEDICAL ATTENTION. INGESTION: FLUSH MOUTH WITH WATER.
  IN  TREATMENT OF AN OVERDOSE, EMESIS OR  LAVAGE OF STOMACH WITH 4% TANNIC
  ACID SOLUTION AND ADMINISTRATION OF ACTIVATED CHARCOAL RECOMMENDED. OBTAIN
  MEDICAL ATTENTION.
*
Handling and Disposal
*
Spill Release Procedures: WEAR APPROVED RESPIRATOR AND CHEMICALLY COMPATIBLE
  WASTE DISPOSAL. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKU P IS
  COMPLETE
Neutralizing Agent: NOT PROVIDED BY MFR
Waste Disposal Methods: DISPOSE IN ACCORDANCE WITH ALL APPLICABLE FEDERAL
  STATE, AND LOCAL LAWS. THIS PRODUCT DOES NOT MEET THE DEFINITION OF HAZARDOUS
Handling And Storage Precautions: STORE IN TIGHT CONTAINER AS DEFINED IN THE
  UNITED STATES PHARMACOPEIA. THIS MATERIAL SHOULD BE HANDLED AND STORED PER
  LABEL AND OTHER INSTRUCTIONS TO ENSURE PRODUCT INTEGRITY. DO NOT PERMIT
  EATING, DR INKING OR SMOKING NEAR MATERIAL.
Other Precautions: AVOID CONTACT WITH EYES, SKIN OR CLOTHING. AVOID BREATHING
  DUST OR MIST. USE WITH ADEQUATE DUST CONTROL. WASH THOROUGHLY AFTER HANDLING.
  DO NOT PERMIT EATING, DRINKING, OR SMOKING NEAR MATERIAL.
*
Fire and Explosion Hazard Information 
*
Extinguishing Media: USE EXTINGUISHING MEDIA APPROPRIATE FOR SURROUNDING FIRE
  CONDITIONS.
Fire Fighting Procedures: WEAR SELF CONTAINED BREATHING APPARATUS AND
  PROTECTIVE CLOTHING.
Unusual Fire/Explosion Hazard: NONE. TOXIC GASES PRODUCED: CARBON OXIDES,
  NITROGEN OXIDES.
*
*
Respiratory Protection: NIOSH/OSHA-APPROVED RESPIRATOR.
Ventilation: USE GENERAL OR LOCAL EXHAUST.
Other Protective Equipment: PROTECT EXPOSED SKIN. APPROPRIATE LABORATORY
  APPAREL. SELF CONTAINED BREATHING APPARATUS SHOULD BE USED WHEN FIGHTING
  FIRES INVOLVING A CHEMICAL.
Work Hygienic Practices: NOT PROVIDED BY MFR
Supplemental Safety and Health: MSDS ALSO COVERS ISOPTO HOMATROPINE, 5% - 5 ML
*
Physical/Chemical Properties 
*
HCC: T6
Decomp Text: NOT PROVIDED BY MFR
PH: NOT PROVIDED
Viscosity: NOT PROVIDED BY MFR
Solubility in Water: ALL COMPONENTS SOLUBLE.
Appearance and Odor: AQUEOUS SOLUTION.
Percent Volatiles by Volume: NOT PROVIDED
Corrosion Rate: NOT PROVIDED BY MFR
*
Reactivity Data 
*
Stability Indicator: YES
Stability Condition To Avoid: MATERIAL IS STABLE FROM A SAFETY POINT OF VIEW.
Materials To Avoid: ALKALIES, IODINE.
Hazardous Decomposition Products: MATERIAL EMITS TOXIC FUMES WHEN HEATED TO
  DECOMPOSITION.
Hazardous Polymerization Indicator: NO
Conditions To Avoid Polymerization: WILL NOT OCCUR.
*
Toxicological Information 
*
Toxicological Information: USED MEDICINALLY ONLY IN THE EYE BT REPORTS OF CNS
  INVOLVEMENT HAVE APPEARED FOLLOWING USE OF HOMATROPINE EYE DROPS. HOMATROPINE
  TROPINE INCLUDE DRYNESS OF THE MOUTH WITH DIFFICULTY IN SWALLOWING, THIRST,
  DILATION OF THE PUPILS WITH LOSS OF ACCOMMODATION AND PHOTOPHOBIA, INCREASED
  INTRAOCULAR PRESSURE, FLUSHING AND DRYNESS OF T HE SKIN, TRANSIENT
  BRADYCARDIA FOLLOWED BY TACHYCARDIA WITH PALPITATIONS AND ARRYTHMIAS.
  POSSIBLE ALLERGIC REACTION TO DUST IF INHALED, INGESTED OR IN CONTACT WITH
  SKIN. POISONOUS.
*
Ecological Information 
*
Ecological: (CONTD, FROM "HEALTH HAZARDS")  INGESTION: THE CONCENTRATION OF
  PRODUCT POSSESSES A SIGNIFICANT ORAL HAZARD TO CHILDREN SHOUL D ACCIDENTAL OR
  INTENTIONAL INGESTION OCCUR. CHRONIC EXPOSURE: POSSIBLE HYPERSENSITIZATION
  AND DEVELOPMENT OF SYSTEMIC EFFECTS NOTED  UNDER ACUTE HAZARDS.
*
*
Transport Information: THIS PRODUCT DOES NOT POSE AN UNREASONABLE RISK TO
  HEALTH AND SAFETY OR PROPERTY WHEN TRANSPORTED IN COMMERCE. THE HAZARD CLASS
*
Regulatory Information 
*
*
Other Information 
*
Other Information: HAZARD RATINGS: HEALTH: 1; FLAMMABILITY: 0; REACTIVITY: 0;
  PPE: NPU. AS A GENERAL RULE, INDIVIDUALS WORKING WITH CHEMICALS SHOULD
  CONSIDER ALL CHEMICALS TO BE POTENTIALLY HAZARDOUS EVEN IF THEIR  INDIVIDUAL
  HAZARDS ARE UNCHARACTERIZED OR UNKNOWN.
*
Transportation Information 
*
Multiple KIT Number: 0
Unit Of Issue: BT
Additional Data: TRANSPORTATION DATA PER MANUFACTURER'S MSDS. THIS PRODUCT DOES
  NOT POSE AN UNREASONABLE RISK TO HEAL TH AND SAFETY OR PROPERTY  WHEN
  ARE NOT APPLICABLE TO THIS PRODUCT.
*
Detail DOT Information 
*
DOT PSN Code: ZZZ
DOT Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION
*
Detail IMO Information 
*
IMO PSN Code: ZZZ
IMO Proper Shipping Name: NOT REGULATED FOR THIS MODE OF TRANSPORTATION
*
Detail IATA Information 
*
IATA PSN Code: ZZZ
IATA Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION
*
Detail AFI Information 
*
AFI PSN Code: ZZZ
AFI Proper Shipping Name: NOT REGULATED BY THIS MODE OF TRANSPORTATION
*
HAZCOM Label 
*
Company Name: ALCON LABORATORIES INC
Label Required IND: Y
Status Code: A
Origination Code: F
Chronic Hazard IND: Y
Skin Protection IND: YES
Signal Word: CAUTION
Respiratory Protection IND: YES
Health Hazard: Slight
Contact Hazard: Slight
Fire Hazard: None
Reactivity Hazard: None
Hazard And Precautions: STORE IN TIGHT CONTAINER AS DEFINED IN U.S.
  PHARMACOPEIA. HANDLE AND STORE PER LABEL AND OTHER INSTRUCTIONS TO ENSURE
  PRODUCT INTEGRITY. DO NOT EAT DRINK OR SMOKE NEAR PRODUCT. AVOID CONTACT WITH
  EYES , SKIN, OR CLOTHING. AVOID BREATHING DUST OR MIST. USE WITH ADEQUATE
  DUST CONTROL. WASH THOROUGHLY AFTER HANDLING. INHALATION: MAY BE IRRITATING
  TO MUCOUS MEMBRANES AND RESPIRATORY TRACT.  EYE CONTACT : PRODUCT CONFORMS TO
  FDA REGULATIONS AND GUIDELINES FOR AN OPHTHALMIC FORMULATION THAT HAS BEEN
  DEMONSTRATED TO BE SAFE FOR USE IN THE EYE.
*
