The top 14 Major League Baseball career strikeout leaders ( through September 26 , 2011 ) : # Reggie Jackson – 2,597 # Jim Thome – 2,486 # Sammy Sosa – 2,306 # Andrés Galarraga – 2,003 # José Canseco – 1,942 # Willie Stargell – 1,936 # Alex Rodriguez –
By August 18 , 2011 , Jim Thome had less than 2,460 strikeouts in his career .