The Top 16 Major League Baseball career strikeout leaders ( through July 24 , 2012 ) : # Reggie Jackson – 2,597 # Jim Thome – 2,530 ( 43 ) # Sammy Sosa – 2,306 # Andrés Galarraga – 2,003 # Alex Rodriguez – 2,000 ( 84 ) # Adam Dunn - 1,955 ( 146 ) # José Canse
On July 24 , 2012 , Jim Thome had more than 2,528 strikeouts in his career , Alex Rodriguez had more than 1,998 , and Adam Dunn had more than 1,953 .