L 65/22 Official Journal of the European Communities 14.3.2000 adapting to technical progress Annex II to Council Directive 76/768/EEC on the approximation of TWENTY-HFTH COMMISSION DIRECTIVE 2000/11/EC of 10 March 2000 the laws of the Member States relating to cosmetic products (Text with EEA relevance) THE COMMISSION OF THE EUROPEAN COMMUNITIES, Having regard to the Treaty establishing the European Community, Having regard to Council Directive 76/768/EEC of 27 July 1976 on the approximation of the laws of the Member States relating to cosmetic products (!), as last amended by Commission Directive 2000/6/EC (%), and in particular Article 8(2) thereof, Having regard to the consultation of the Scientific Committee on Cosmetic Products and Non-Food Products intended for Consumers, Whereas: 1 It is an established fact that 3'-ethyl-5',6',7',8'-tetrahydro-5',5',8',8'-tetramethyl-2'"-acetonaphthone or 7-acetyl-6-cthyl-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphtalen is a substance that induces neuro- toxic effects. This substance should therefore be prohibited in cosmetic products, and it should be listed in Annex II to the abovementioned Directive. It is an established fact that aristolochic acid and its salts, as well as Aristolochia spp. and their preparations, are substances that act as powerful carcinogens. These substances should therefore be prohibited in cosmetic products, and they should be listed in the abovementioned Annex IL It is an established fact that 2,3,7,8-tetra chlorodibenzo-p-dioxin is a toxic substance with powerful cancer-causing potential. This substance should therefore be prohibited in cosmetic products, and it should be listed in the abovementioned Annex II It is an established fact that 6-(piperidinyl)-2,4-pyrimidinediamine 3-oxide (minoxidil) and its salts are substances that produce powerful systemic vasodilating effects. Furthermore, a special scientific assessment needs to be made of minoxidil derivatives in order to determine their possible effects on health. Minoxidil and its salts should therefore be prohibited in cosmetic products, and they should be listed in the abovementioned Annex IL It is an established fact that 3,4',5-tribromosalicylanilide is a substance that produces a powerful and prolonged photosensitising effect. This substance should therefore be prohibited in cosmetic products, and it should be listed in the abovementioned Annex IL It is an established fact that Phytolacca spp. and their preparations are toxic substances that produce adverse pharmacological effects. These substances should therefore be prohibited in cosmetic prod- ucts, and they should be listed in the abovementioned Annex IIL It is an established fact that 11a-hydroxypregn-4-ene-3, 20-dione) and its esters are substances that produce endocrine activity levels in correlation with powerful hypertension effects. These substances should therefore be prohibited in cosmetic products, and they should be listed in the above- mentioned Annex IL It is an established fact that the colouring agent C.I. 42 640 is a substance that produces carcinogenic effects. This substance should therefore be prohibited in cosmetic products, and it should be listed in the abovementioned Annex II 262, 27.9.1976, p. 169. oL 0] L 56, 1.3.2000, p. 42.