 Pari gbolohun ti o tẹle: Ni ọjọ 5 Oṣu Karun ọdun 2019, a yan Lopetegui gẹgẹbi oludari tuntun ti Sevilla FC lori adehun ọdun mẹta kan. Ni ọdun akọkọ rẹ, wọn pari kẹrin lati ni ẹtọ fun Champions League, ati ni Oṣu Kẹjọ Ọjọ 21 wọn ṣẹgun Inter Milan 32 ni : 2020 UEFA Europa League Final, ẹyẹ àkọkọ fún ẹgbẹ rẹ. 