 Complete the following phrase:  The overthrow of the Shah of Iran in 1979 was a major setback for the policy. The Islamic regime of Iran severed relations with Israel, and its leaders such as Ruhollah Khomeini, Ali Khamenei and Mahmoud Ahmadinejad have repeatedly called it an illegal entity and even advocate its destruction. The doctrine led to questionable attempts by Israel to establish good relations with the avowedly anti-zionist Islamic Republic of Iran after the 