 Complete the following phrase:  Portugal formed the first European colonial Empire in 1415 with the conquest of Ceuta. In 1453, the French expelled the English from their land and the Ottoman Turks caused the Fall of Constantinople, initiating the rise of the Ottoman Empire in Europe. At the end of the 15th century, Spain was formed following the marriage of Isabella I of Castile and Ferdid II of Aragon. Portugal and Spain, followed by France and England, ushered the Age of Discovery. During the early 16th century, France and the Habsburg clashed during the Italian Wars. In 1519, Charles V of Habsburg, already Duke of Burgundy, King of Spain, and Archduke of Austria, became Holy Roman Emperor and initiated a long rivalry with Francis I of France and the Ottoman sultan Suleiman the Magnificent. He ordered the conquistadores to annex the Aztec Empire and 