 Complete the following phrase:  The plague returned at intervals with varying virulence and mortality until the early 19th century. In England, for example, the plague returned in 136063, killing 20 of Londoners, and in 1369, killing 1015. At the end of the 16th century, the plague hit San Cristóbal de La Laguna 158283 in the Canary Islands. In the 17th century, outbreaks were a series of great plagues: the Great Plague of Seville 164752, the Great Plague of London 166566 and the 