 Complete the following phrase:  The Spanish Empire conquered the region in the 16th century and established a viceroyalty that encompassed most of its South American territories, with its capital in Lima. Higher education started in the Americas with the official establishment of the National University of San Marcos in Lima in 1551. Peru formally proclaimed independence in 1821, and following the foreign military campaigns of José de San Martín and Simón Bolívar, and the decisive battle of Ayacucho, Peru 