 Complete the following phrase:  In 1585, as relations between England and Spain worsened after Mary Queen of Scots was beheaded in which the latter had supported. King Philip II of Spain ordered an invasion of England and set about building what would become the Spanish Armada at the naval shipyards of Cádiz. Elizabeth once again authorized Francis Drake to disrupt Spanish shipping - he sacked Santo Domingo and Cartagena, which became the opening salvo of the Anglo-Spanish War 15851604. Further disruption then took place at Cadiz in 1587; Drake 