The "Air Force One" call sign was created after a 1953 incident during which a Lockheed Constellation named Columbine II, carrying President Dwight D. Eisenhower, entered the same airspace as a commercial airline flight using the same flight number.\n\nWho was the first president to use air force one?
Steam of consciousness below:

User
The relevant information to answer the above question is: The "Air Force One" call sign was created after a 1953 incident during which a Lockheed Constellation named Columbine II, carrying President Dwight D. Eisenhower, entered the same airspace as a commercial airline flight using the same flight number.
So, the answer is President Dwight D. Eisenhower.
Assistant