Passage: Paracelsus (1493 -- 1541) developed the concept, writing that "Nature marks each growth ... according to its curative benefit", and it was followed by Giambattista della Porta in his Phytognomonica (1588).\n\nQuestion: Based on this passage, who came up with the doctrine of signatures? Let's have some stream of consciousness first.
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The relevant information is: Paracelsus (1493 -- 1541) developed the concept, writing that "Nature marks each growth ... So, the answer is Paracelsus.
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