 The rise of the cognitive paradigm in immunology originated in conceiving the immune system as a faculty of perception. Immunologists explicitly describe macrophages “seeing” antigen; antibodies “recognizing” epitopes; T cell possessing “memory”; and adaptive immunity comprising a “learning” process. Such extensions from human psychology have been widely utilized in evolutionary history (Margulis, Asikainen, and Krumbein 2011), wherein basic categories of human cognition have been extrapolated to animals (Bekoff, Allen, and Burghardt 2002), bacteria (Ben Jacob et al. 2004; Ben Jacob, Shapira, and Tauber 2005), cancer cells (Ben Jacob, Coffey, and Levine 2012) and the immune system (Cohen 1992a, 1992b). The influence of the cognitive metaphor (where intention plays an incipient role) appears throughout immune theory with extrapolations to cognitive science more generally (Varela 1994: 36; Varela et al. 1988; Varela and Coutinho 1991; Vaz 2011b).