  As we saw in section 2, Quine takes the fundamental epistemological problem to be that of showing how we come to have knowledge of the world. He seeks an account which is naturalistic in his austere sense, and thus starts with the idea that we know about the world only from impacts of various forms of energy on our sensory nerves (see 2.3, above). How do we get from such impacts to something recognizable as knowledge of the world? In the words of the title of Quine’s last monograph: how do we get from stimulus to science?