 The empiricists methodology is not without problems. The biggest issue is that all knowledge becomes probabilistic and a posteriori. Immanuel Kant (1724–1804) was one of the first to point out that the human mind has a grasp of the meta-concepts of space, time and causality that itself can never be understood as the result of a mere combination of “ideas”. What is more, these intuitions allow us to formulate scientific insights with certainty: i.e., the fact that the sum of the angles of a triangle in Euclidean space is 180 degrees. This issue cannot be explained in the empirical framework. If knowledge is created by means of combination of ideas then there must exist an a priori synthesis of ideas in the human mind. According to Kant, this implies that the human mind can evaluate its own capability to formulate scientific judgments. In his Kritik der reinen Vernunft (1781) Kant developed transcendental philosophy as an investigation of the necessary conditions of human knowledge. Although Kant’s transcendental program did not contribute directly to the development of the concept of information, he did influence research in to the foundations of mathematics and knowledge relevant for this subject in the nineteenth and twentieth century: e.g., the work of Frege, Husserl, Russell, Brouwer, L. Wittgenstein, Gödel, Carnap, Popper and Quine.