 Suggestions have been made to use the term “gene” to refer to the whole process that yields the functional product (the “process molecular gene” concept, Neumann-Held 1999). But apart from the fact that it is difficult to delineate the boundaries of such a process, this seems to be too distant from the ways researchers use the term. Biologists and philosophers have suggested alternative terminologies for DNA sequences that are meant to replace or complement the problematic term gene, for instance, regarding genome evolution (Brosius &amp; Gould 1992), regulation (Scherrer &amp; Jost 2007), and from an integrative systems perspective (Keller &amp; Harel 2007). While some of these interventions seem to suggest that the gene concept has become redundant, biologists have emphasized its explanatory value when seen in the right context, in particular, as a cellular component (Hall 2001). It might be the case that this component of cells has received undue attention to the expense of others, but it must also be noted that genes (or DNA) are often in focus because they can be most easily intervened on, while these interventions can then also be informative about other components of cellular processes (Gannett 1999; Waters 2008). Similarly, in the practical contexts of synthetic biology, genes can often successfully be constructed, conceptually and materially, as causal agents (Oftedal &amp; Parkkinen 2013). More generally, it has been suggested that the gene concept is useful exactly because of its overall vagueness, because it can be adjusted to specific epistemic needs within newly emerging fields and at the same time facilitate connections between disparate areas of research (Rheinberger &amp; Müller-Wille 2018).