The new mechanical philosophy and, more generally, attention to the framework concept of “mechanism” has expanded rapidly over the last two decades bringing with it new orientations toward a wide range of issues in the philosophy of science. Yet it is clear that many of the major topics are only beginning to develop, leaving a lot of work for scholars to elaborate the basic commitments of this framework and to consider what it means to do science outside of that framework.  The near future is likely to see continued discussion of the implications and limits of this framework for thinking about science and scientific practice.