 The new scientific interest in meditation (especially mindfulness), the new cultural interest in meditating for limited psychological or physiological benefits rather than transforming one’s entire character, and the utilization of psychedelics in psychotherapy have given rise today to a new phenomenon — “secular mysticism.” Awe and wonder at nature is prominent, but this mysticism is not a matter of “nature mysticism” or of aesthetic experiences as possible triggers of mystical experiences. Rather, the interest is in the psycho-physiological effects of meditation and psychedelics, with mystical experiences understood within a naturalist framework. Neuroscience appears to validate the positive effects of meditation and psychedelics on our well-being. Secular forms of meditation for limited benefits, such as Jon Kabat-Zinn’s mindfulness-based stress reduction program. Secularists can disconnect traditional practices from a mystical tradition (e.g., Batchelor’s “secular Buddhism” [2015]) or focus only on limited practices (e.g., Harris 2014, Letheby 2017).