 Research-related concerns such as these have led to upheavals within psychiatry, issuing in new, dimensional criteria by which the research domain is to be approached (Revised Domain Criteria, or RDoC). Separate units of analysis (genes, cells, circuits, self reports, etc.) are each employed in specific research domains (such as positive and negative valence systems, cognitive systems, systems for social processes, and arousal/regulatory systems), and the intersections of units of analysis with research domains produce segments of a spectrum linking normal and atypical features. Although whether the following goals are entirely compatible has been questioned, the aim here is to promote both more accurate research and more effective treatments (Cuthbert &amp; Insel 2013; Perring 2016). And while answering some of the concerns about the earlier classificatory model, RDoC has in its turn been criticized for, among other features, its conception of validity; its assumptions about the uniformity of normal distributions; its continuing acceptance of clinical and medical presuppositions assigning disorder to the individual rather than the broader social context; and its finding little place for personal agency, and assuming a traditional, individualistic and autonomous model of self challenged by today’s philosophical analyses. (See essays in Poland &amp; Tekin 2017.)