These strands began to coalesce into an over-arching perspective in the 1990s. The earliest clear statement of the new mechanism was Bechtel and Richardson’s (2010 [1993]) Discovering Complexity. They self-consciously put aside logical empiricist concerns with theory reduction and focused instead on the process by which scientists discover mechanisms (see Section 6 below). Soon after, Glennan argued that mechanisms are the secret connexion Hume sought between cause and effect (1996), a thesis related to and partly inspired by Cartwright’s focus on capacities and nomological machines (Glennan 1997). Likewise, Thagard’s How Scientists Explain Disease centered the search for causes and mechanisms in medicine (Thagard 2000; see also Section 6 below). Machamer, Darden and Craver’s “Thinking about Mechanisms” (Machamer, Darden, and Craver 2000; familiarly known as “MDC”) drew these strands together and became for many the lightening rod of the new mechanist perspective. MDC suggested that the philosophy of biology, and perhaps the philosophy of science more generally, should be restructured around the fundamental idea that many scientists organize their work around the search for mechanisms.