 Systems biology can be interpreted as a response to limitations of research strategies investigating molecules and pathways in isolation. To clarify the significance of their approach, systems biologists often stress the need to complement or go beyond what is perceived as reductionist strategies in molecular biology (De Backer et al. 2004; van Regenmortel 2004). The contrast between systems biology and molecular biology should not be overstated (see also  Section 4.1).  However, the contrasting comparison reveals how systems biology is motivated by the need for a theoretical framework that is better suited for studying the dynamics and organization of many interconnected components (Boogerd et al. 2007; Kitano 2001).