 Philosophers and scientists alike have debated the implications of research focusing on generic properties of biological networks, rather than the properties of specific molecular components (e.g., Barabási 2002; Bechtel 2015a,b; Craver 2016). Among the controversial issues is how the enhanced focus on topological properties relates to more traditional mechanistic explanations in biology  (Section 4.2).  A related issue is whether functional capacities can be derived from an analysis of network architectures alone. Some systems biologists and philosophers have pointed to the limitations and possible biases associated with inferences of functions from automated pattern-detection in datasets (Calvert 2012; Keller 2005; Krohs 2012; see also Prill et al. 2010). Specifically, some have called for a more dynamic approach that can account for the context of the whole network and how it changes over time.