  All these restrictions notwithstanding, Aristotle can claim that the principle of causational synonymy remains universally valid. This is so, because all the three restrictions above specify cases where Aristotle can claim that a preceding, more prominent cause has already satisfied the requirement: in the case of second actualities the first actuality was called into existence by a synonymous cause in the first place; locomotions, qualitative and quantitative changes, even if not caused by a synonymous entity, can be part of a larger pattern of causation, in which a substance is caused by a substance of the same kind; and causal chains producing substances can be claimed to start out invariably from synonymous substances.  