  The image of genetics that emerges from the anti-reductionist literature is of a two-tiered science composed of two discreet theoretical discourses, one grounded in principles about entities at the cytological level (such as chromosomes) and the other grounded in principles about entities at the molecular level (such as nucleotide sequences in DNA). Anti-reductionists believe some phenomena, including transmission of genes, are best explained by a theory grounded at the cytological level and other phenomena, including the expression of genes, are best explained by a theory grounded at the molecular level. Although Kitcher argues that classical genetics provides the best explanation in an objective sense, some anti-reductionists (e.g., Rosenberg 1985, 1994) believe that the obstacles to reduction are merely practical. Rosenberg (1985, 1994) appealed to the concept of supervenience to argue that in principle, molecular genetics would provide the best explanations. But he argued that in practice, classical genetics provides the “best” explanation of transmission phenomena, in the sense that this is the best explanation available to creatures with our cognitive limitations. Subsequently, however, Rosenberg changed his position on this issue, largely on the grounds that that technological advances in information storage and processing "may substantially enhance our capacity to understand macromolecular processes and their combinations" (Rosenberg 2006, p. 14).