 The argument from explanatory regress focuses on the tenability of a standard reason for holding that holist explanations should be dispensed with. The standard reason in question is the following. Given that holist explanations focus on larger units in the form of social entities and processes, they are less preferable than individualist explanations that zero in on the components of these larger units, viz. individuals, their actions, etc. The argument from explanatory regress states that this claim may likewise be used to justify the contention that individualist explanations are less preferable than explanations that focus on the biological components of individuals. The claim may be further used to motivate the assertion that these explanations, too, should be dismissed in favor of explanations that concentrate on the chemical components of individuals’ biological units, and so on. To avoid this undesirable consequence, the argument continues, the standard reason for holding that holist explanations are always less preferable than individualist ones should be dismissed. Accordingly, since explanatory practices should not be changed unless there are good reasons to do so, the existing practice of offering holist explanations should not be discontinued. From the perspective of carrying on existing explanatory practices, holist explanations are indispensable.