 Given the ubiquitous institutional pleas for more interdisciplinary research, a crucial task for pluralist philosophers is to investigate when interactive and integrative approaches may be more successful than isolationist or reductionist ones. Most attempts at addressing this issue have been domain specific and often push at the end for integration of explanations (e.g., McCauley &amp; Bechtel 2001 on psychology and neuroscience, Kendler 2005 on psychiatry, Mitchell 2009 on social insect behavior). By contrast, limitations to integrative tendencies have been identified as resulting from general considerations on the very structure of explanations (Gijsbers 2016). In any case, much more philosophical work needs to be done on the notion of integration, what exactly it amounts to in practice and under which conditions it may succeed (Muszynski &amp; Malaterre 2020).