 While intersectional theorists bring forward race, class, ability, and other socioeconomic markers as central to psychical-historical locations of agency, power, and connectivity, a number of feminists are increasingly paying attention to somatic and organic factors in selfhood. In addition to the revaluing of embodiment in affect theory and new materialisms mentioned above  (section 2),  Catherine Malabou points to mental ailments such as Alzheimer’s disease to press upon poststructuralist and psychoanalytic theories of selfhood (Malabou 2012). Diseases with a physical basis challenge any conception of subjectivity located exclusively in the psychic continuities of conscious and/or unconscious life as posited by psychoanalytic theory. Malabou reinterprets Derrida’s deconstructive self as punctured by experiences of alterity through a non-reductive neurobiology of trauma and brain injury. Injured selves may experience radical discontinuities or lose entirely aspects of their former selves. The resulting picture of the self is a multilayered nexus of relations with psychic-historical and somatic-organic strata. Her work makes clear that feminist philosophies of the self cannot ignore the biological sciences.