 At the experimental level, instruments, as found objects, acquire new meanings, developments and uses as they bridge over the transitions between theories, observations or theory-laden observations. Instruments and experimental projects in the case of Big Science also bring together, synchronically and interactively, the skills, standards and other resources from different communities, and change each in turn (on interdisciplinary experimentation see also Osbeck et al. 2011). Patterns of laboratory research are shared by the different sciences, not just instruments but general strategies of reconfiguration of human researchers and natural entities researched (Knorr-Cetina 1992), statistical standards (e.g., statistical significance) and ideals of replication. At the same time, attention has been paid to the different ways on which experimental approaches differ among the sciences (Knorr-Cetina 1992, Guala 2005, Weber 2005) but also to how they have been transferred (e.g., field experiments and randomized control trials) or integrated (e.g., mixed methods combining quantitative and qualitative techniques). 