 This comprehensive, uniform rigidity in turn undermines other features attributed to levels of organization. One of these features is the supposed epistemic merit (or fault) inherently exhibited by natural constituents due to their position at a particular level (Potochnik &amp; McGill 2012. 129–30). For instance, reductionists frequently argue that molecular-level explanations are generally more secure, more fundamental, or otherwise superior to explanations citing higher-level structures like chromosomes or cells (and conversely, anti-reductionists claim that higher-level constituents are often necessary for producing adequate explanations). However, as has been pointed out by many authors, blanket attributions of significance like these are deeply misleading (e.g., Wimsatt 1976a; Jackson &amp; Pettit 1992; cf. Potochnik &amp; McGill 2012: 129; Noble 2012: 56; Craver 2007: 191). One reason for this is that particular levels exhibit epistemic merit only in regard to what is being investigated. As such, what is taken to be the relevant level will shift depending on what structures or processes comprise the focus of scientists’ investigative tasks, and hence no level will have inherent or principled epistemic superiority. Moreover, epistemic products like explanations and theories in biology rarely exhibit a monolevel structure, but rather include multiple levels simultaneously (e.g., Schaffner 1993: 97–8, 387; Mitchell 2003: 147; Craver 2007).