  After thirteen years in Athens, Aristotle once again found cause to retire from the city, in 323. Probably his departure was occasioned by a resurgence of the always-simmering anti-Macedonian sentiment in Athens, which was free to come to the boil after Alexander succumbed to disease in Babylon during that same year. Because of his connections to Macedon, Aristotle reasonably feared for his safety and left Athens, remarking, as an oft-repeated ancient tale would tell it, that he saw no reason to permit Athens to sin twice against philosophy. He withdrew directly to Chalcis, on Euboea, an island off the Attic coast, and died there of natural causes the following year, in  322.[3]