 Deplazes (2009) has suggested the following extended classification of practices within synthetic biology: i) bioengineering, ii) synthetic genomics, iii) protocell synthetic biology, iv) unnatural molecular biology, and v) in silico approaches (see  Figure 3).  While the categories of work on protocells and synthetic genomes overlap with the categorization by O’Malley et al. (2008), DNA-based device construction is here further divided into bioengineering (exemplified by assembly standards like BioBricksTM) and unnatural molecular biology. Unnatural molecular biology aims to create systems with different components, e.g., artificial nucleic acids based on a different coding system. Philosophers have debated whether the term ‘unnatural’ distinguishes practices in synthetic biology from other bioengineering approaches (Lewens 2013; Preston 2013). But the emphasis on synthetic artifacts underscores the affinity to synthetic chemistry and perhaps also to the ‘chemist style of thinking’, emphasizing synthesis and invention in addition to analysis and discovery (Bensaude-Vincent 2009, 2013, 2015; see also Bursten 2020, ed.).