 In current cognitive science, human cognition is often explored in terms of model-based reasoning. The starting point of this approach is the notion that much of human reasoning, including probabilistic and causal reasoning as well as problem solving takes place through mental modeling rather than through the application of logic or methodological criteria to a set of propositions (Johnson-Laird 1983; Magnani et al. 1999; Magnani and Nersessian 2002). In model-based reasoning, the mind constructs a structural representation of a real-world or imaginary situation and manipulates this structure. In this perspective, conceptual structures are viewed as models and conceptual innovation as constructing new models through various modeling operations. Analogical reasoning—analogical modeling—is regarded as one of three main forms of model-based reasoning that appear to be relevant for conceptual innovation in science. Besides analogical modeling, visual modeling and simulative modeling or thought experiments also play key roles (Nersessian 1992, 1999, 2009). These modeling practices are constructive in that they aid the development of novel mental models. The key elements of model-based reasoning are the call on knowledge of generative principles and constraints for physical models in a source domain and the use of various forms of abstraction. Conceptual innovation results from the creation of new concepts through processes that abstract and integrate source and target domains into new models (Nersessian 2009).