 This entry has addressed six major clusters of problems that threaten the possibility of moral knowledge. Subject to the constraints noted at the outset, the aim has been to examine these problems with an eye to their complexity, especially their mutual ramifications, and to explore avenues of possible resolution that are evident in the philosophical and interdisciplinary literature. From this survey, we can see that for each cluster of problems there are avenues of resolution worth further exploration, especially given interdisciplinary research implying that moral knowledge is deeply social.