 These cyborgization thought experiments can be linked to the Chinese Room. Suppose Otto has a neural disease that causes one of the neurons in my brain to fail, but surgeons install a tiny remotely controlled artificial neuron, a synron, along side his disabled neuron. The control of Otto’s neuron is by John Searle in the Chinese Room, unbeknownst to both Searle and Otto. Tiny wires connect the artificial neuron to the synapses on the cell-body of his disabled neuron. When his artificial neuron is stimulated by neurons that synapse on his disabled neuron, a light goes on in the Chinese Room. Searle then manipulates some valves and switches in accord with a program. That, via the radio link, causes Otto’s artificial neuron to release neuro-transmitters from its tiny artificial vesicles. If Searle’s programmed activity causes Otto’s artificial neuron to behave just as his disabled natural neuron once did, the behavior of the rest of his nervous system will be unchanged. Alas, Otto’s disease progresses; more neurons are replaced by synrons controlled by Searle. Ex hypothesi the rest of the world will not notice the difference; will Otto?  If so, when? And why?