 Jonathan Dancy has well highlighted a kind of contextual variability in moral reasons that has come to be known as “reasons holism”: “a feature that is a reason in one case may be no reason at all, or an opposite reason, in another” (Dancy 2004). To adapt one of his examples: while there is often moral reason not to lie, when playing liar’s poker one generally ought to lie; otherwise, one will spoil the game (cf. Dancy 1993, 61). Dancy argues that reasons holism supports moral particularism of the kind discussed in  section 2.2,  according to which there are no defensible moral principles. Taking this conclusion seriously would radically affect how we conducted our moral reasoning. The argument’s premise of holism has been challenged (e.g., Audi 2004, McKeever &amp; Ridge 2006). Philosophers have also challenged the inference from reasons holism to particularism in various ways. Mark Lance and Margaret Olivia Little (2007) have done so by exhibiting how defeasible generalizations, in ethics and elsewhere, depend systematically on context. We can work with them, they suggest, by utilizing a skill that is similar to the skill of discerning morally salient considerations, namely the skill of discerning relevant similarities among possible worlds. More generally, John F. Horty has developed a logical and semantic account according to which reasons are defaults and so behave holistically, but there are nonetheless general principles that explain how they behave (Horty 2012). And Mark Schroeder has argued that our holistic views about reasons are actually better explained by supposing that there are general principles (Schroeder 2011). 