  Connected with Peirce’s anti-foundationalism is his insistence on the fallibility of particular achievements in science. Although the scientific method will eventually converge to something as a limit, nevertheless at any temporal point in the process of scientific inquiry we are only at a provisional stage of it and cannot ascertain how far off we may be from the limit to which we are somehow converging. This insistence on the fallibilism of human inquiry is connected with several other important themes of Peirce’s philosophy. His evolutionism has already been discussed: fallibilism is obviously connected with the fact that science is not shooting at a fixed target but rather one that is always moving. What Peirce calls his “tychism,” which is his anti-deterministic insistence that there is objective chance in the world, is also intimately connected to his fallibilism. (Tychism will be discussed below.) Despite Peirce’s insistence on fallibilism, he is far from being an epistemological pessimist or sceptic: indeed, he is quite the opposite. He tends to hold that every genuine question (that is, every question whose possible answers have empirical content) can be answered in principle, or at least should not be assumed to be unanswerable. For this reason, one his most important dicta, which he called his first principle of reason, is “Do not block the way of inquiry!”