 But philosophers have also raised challenges to the causal-mechanical approach. One complaint has been that mechanistic explanations don’t work well in systems biology, a field distinct from molecular biology but that nonetheless draws on the work of molecular biologists. While some argue that systems biology is best explained using mechanisms (cf. Boogerd et al. 2007; Matthiessen 2017; Richardson and Stephan 2007; Bechtel 2011; Bechtel and Abrahamsen 2013), others argue that it requires non-mechanistic explanation (cf. Braillard 2010; Kuhlmann 2011; Silberstein and Chemero 2013).