  Vance (1996) offers a more thorough shift in attention from theory to investigative practice. He asserts that there is only one contemporary science of genetics and describes how investigative methods of classical genetics are an essential part of the methodology of what is called molecular genetics. He concludes that reductionism fails because contemporary genetics still depends on methods of classical genetics involving breeding experiments.  Vance's picture of genetics is compelling. The laboratory methods of classical genetics do indeed persist, even as they are greatly extended, augmented, and often replaced by techniques involving direct intervention on DNA. But Vance's picture does not match the anti-reductionist image of a two-tiered science and the contention that classical genetics will remain aloof from the reductive grasp of molecular biology.