 The Principle of the Infinitesimal Method is perhaps most significant for how it presents a detailed illustration of what the critique of knowledge done according to the transcendental method looks like. The book is a philosophically critical history of the development of calculus. In it, Cohen aims to establish the validity of calculus’ foundational concepts – concepts such as limit and infinitesimal – in the face of philosophical objections against them. He also aims to establish a connection between the concept of infinitesimals and natural science’s capacity to represent reality. In fact, these two aims are connected. For Cohen, the concept of an infinitesimal magnitude is valid for use in calculus, because it is a necessary condition of the possibility of natural science’s representation of real objects. (See Edel 2010, Richardson 2006, Giovanelli 2011, Giovanelli 2016, and Edgar forthcoming).