 The logical empiricists paid little attention to the distinction between observing and experimenting and its epistemic implications. For some philosophers, to experiment is to isolate, prepare, and manipulate things in hopes of producing epistemically useful evidence. It had been customary to think of observing as noticing and attending to interesting details of things perceived under more or less natural conditions, or by extension, things perceived during the course of an experiment. To look at a berry on a vine and attend to its color and shape would be to observe it. To extract its juice and apply reagents to test for the presence of copper compounds would be to perform an experiment. By now, many philosophers have argued that contrivance and manipulation influence epistemically significant features of observable experimental results to such an extent that epistemologists ignore them at their peril. Robert Boyle (1661), John Herschell (1830), Bruno Latour and Steve Woolgar (1979), Ian Hacking (1983), Harry Collins (1985) Allan Franklin (1986), Peter Galison (1987), Jim Bogen and Jim Woodward (1988), and Hans-Jörg Rheinberger (1997), are some of the philosophers and philosophically-minded scientists, historians, and sociologists of science who gave serious consideration to the distinction between observing and experimenting. The logical empiricists tended to ignore it. Interestingly, the contemporary vantage point that attends to modeling, data processing, and empirical results may suggest a re-unification of observation and intervention under the same epistemological framework. When one no longer thinks of scientific observation as pure or direct, and recognizes the power of good modeling to account for confounds without physically intervening on the target system, the purported epistemic distinction between observation and intervention loses its bite.