 Human beings make history; but what is the fundamental nature of the human being? Is there one fundamental “human nature,” or are the most basic features of humanity historically conditioned (Mandelbaum 1971)? Can the study of history shed light on this question? When we study different historical epochs, do we learn something about unchanging human beings—or do we learn about fundamental differences of motivation, reasoning, desire, and collectivity? Is humanity a historical product? Giambattista Vico’s New Science (1725) offered an interpretation of history that turned on the idea of a universal human nature and a universal history (see Berlin 2000 for commentary). Vico’s interpretation of the history of civilization offers the view that there is an underlying uniformity in human nature across historical settings that permits explanation of historical actions and processes. The common features of human nature give rise to a fixed series of stages of development of civil society, law, commerce, and government: universal human beings, faced with recurring civilizational challenges, produce the same set of responses over time. Two things are worth noting about this perspective on history: first, that it simplifies the task of interpreting and explaining history (because we can take it as given that we can understand the actors of the past based on our own experiences and nature); and second, it has an intellectual heir in twentieth-century social science theory in the form of rational choice theory as a basis for comprehensive social explanation.