 Some works of these theologians can be seen as vast, overflowing commentaries on a number of questions from the Summa theologiae, especially on topics such as law and justice. Since they were confronted by a rapidly changing universe—the New World, populated by inhabitants who belonged to none of the traditionally known religions, and a globalizing economy (including the slave trade)—they had to deal with new opportunities and new problems, while still considering long-standing questions such as the legitimacy of charging interest. Because they were understood, or understood themselves, as confessors or as advisors of confessors—Domingo de Soto was Emperor Charles V’s confessor, Luis de Molina declared that he wrote for the confessors of those who hold power—they had to cope with political, economic, and legal reality, often in a quite detailed manner.