 Nor did Gómez Pereira accept the concept of prime matter. The procedure which Aristotle followed to conceive this concept was none other than analogy, because prime matter is not accessible to the senses. It is something that remains as an immutable subject in the transition from one form to another one; for instance, if a new form must be induced during the process of generation, then the natural dispositions required for the formation of the new living being must be precedent and remain during all this process; those dispositions, inaccessible to sensory perception, are prime matter, which lacks any positive nature. Hence Aristotle pointed out in Metaphysics VII that it is not a quid or a quantum, or any other genre of predicates (see Metaphysica, VII, 3, 1029a6–29). Against this theory, the author of the Antoniana Margarita argued that in the process of natural generation it is observed not only that the material part of the compound disappears, but also the formal one, so if the sentence ex nihilo nihil fieri is adopted by the Aristotelians for affirming the necessary permanence of matter, the same should be said with respect to the form, since neither the form nor matter can turn into nothing or be generated from nothing: this means then that also the form would exist in a temporal continuum (AM: I.549). In Pereira’s opinion, this problem can be easily solved if we consider that the elements are the basic materials of nature. They can perfectly play the role of matter, and there is no problem in the fact that the elements are also subject to mutation and even annihilation, because, ultimately, they are under the influence of qualities which are contrary to their own consistency: so when these qualities have a strong presence in them, this always leads to their destruction; but, on the contrary, whenever the primary qualities appear in the right proportion, the same elements are generated again.