 In the United States, the various regulatory agencies who have signed on to the Common Rule (45 C.F.R. 46 Subpart A) have not issued formal guidance on Internet research (see the links in the Other Internet Resources section, under Laws and Government Documents). The Preamble to the Revised Rule referenced significant changes in the research environment, recognizing a need to broaden the scope of the Rule. However, substantial changes to the actual Rule in regards to Internet research in its broadest context, were minimal.