 In general, because dualities are transformations between theories, their implications are more radical than those of symmetry transformations. While symmetries are mapping between the solutions of the same theory, different theoretical descriptions can have very different interpretations in terms of objects, properties, degrees of freedom, and spacetime frameworks. Thus, dualities naturally offer a new and interesting viewpoint on many traditional issues in the philosophy of science, such as a) reduction, emergence, and fundamentality; b) theoretical equivalence and underdetermination; and c) realism versus anti-realism. 