 Epigenetic inheritance occurs when environmentally-induced and developmentally-regulated variations, or variations that are the result of developmental noise, are transmitted to subsequent generations of cells or organisms (Jablonka &amp; Lamb 2005). The term epigenetic inheritance is used in a broad sense and in a narrow sense. The narrow sense refers to the systems that underlie cellular heredity. Four EISs in the narrow sense are discussed by Jablonka and Lamb (2005/2014): (1) Self-sustaining steady-states of metabolic cycles. Transmission of the components of the cycle, such as proteins and metabolites, can lead to reconstruction of the cycle in the daughter cell. Self-sustaining loops can also maintain the transcription levels of genes. For example, a transcriptional self-sustaining loop is most likely responsible for white-opaque switching in Candida albicans, a change in phenotypic state that involves a change in cell appearance, mating behavior, and preferred host tissues that is heritable for many generations. (2) Structural inheritance of cell structures, such as cellular membranes and the cilia on the cell surface of ciliates. (3) Chromatin marking of various kinds that consists of molecular marks on chromosomes (specifically, DNA methylation and histone modifications, which involve chemical groups attached to DNA and to proteins around which the DNA molecules are wrapped in eukaryotic cells). Some of these marks are copied by dedicated copying machinery, others seem to be reconstructed as a result of regular genome dynamics from partial markings transmitted to daughter cells (e.g., Henikoff, Furuyama, &amp; Ahmad 2004; reviewed in Lamm 2014). (4) Inheritance of small RNA molecules that affect gene expression. The most well-known case involves RNA silencing (RNAi), a post-transcriptional silencing mechanism, though more and more classes of regulatory RNA molecules and related pathways are being identified and characterized.