 These experiments involve microstimulation of small populations of neurons that are targeted precisely because of their informational content. Microstimulation involves injecting a small current from the tip of an electrode inserted into brain tissue that directly stimulates nearby neurons or, through synaptic connections to other neurons, indirectly activates more distant neurons (see Histed, Ni, &amp; Maunsell 2013 for a review). It is assumed that neurons tuned in similar ways, that is neurons that respond to similar stimuli, tend to be interconnected, so microstimulation is taken to largely drive similarly tuned neurons.