  It is worth noting that in Quine’s writings there are at least two holist themes. The first is the confirmational holism discussed above (often called the Quine-Duhem thesis). The other is semantic holism which is the view that the unit of meaning is not the single sentence, but systems of sentences (and in some extreme cases the whole of language). This latter holism is closely related to Quine’s well-known denial of the analytic-synthetic distinction (Quine 1980b) and his equally famous indeterminacy of translation thesis (Quine 1960). Although for Quine, semantic holism and confirmational holism are closely related, there is good reason to distinguish them, since the former is generally thought to be highly controversial while the latter is considered relatively uncontroversial.