 In 1634, while Galileo was confined to his villa in Arcetri, his beloved eldest daughter died (Sobel 1999). Around this time, he began work on his final book, Discourses and Mathematical Demonstrations Concerning Two New Sciences, based on the mechanics he had developed early in his career. The manuscript was smuggled out of Italy and published in Holland by the Elzeviers in 1638. Galileo died early in 1642, and due to his condemnation, his burial place was obscure until he was re-interred in 1737.