  Willard Van Orman Quine (1908–2000) worked in theoretical philosophy and in logic. (In practical philosophy—ethics and political philosophy—his contributions are negligible.) He is perhaps best known for his arguments against Logical Empiricism (in particular, against its use of the analytic-synthetic distinction). This argument, however, should be seen as part of a comprehensive world-view which makes no sharp distinction between philosophy and empirical science, and thus requires a wholesale reorientation of the subject.