Feminist critique also addresses the fundamental theory of mainstream bioethics. Feminist-friendly bioethicists have noted systemic weaknesses in the explanatory framework that grounds the bioethical analysis of research and clinical practices and increasingly also of public health measures. Critics fault both the abstract character of much bioethical theory and inattention to such key components of morality as the contexts that frame health care and the relational networks that inform patient decision making. The tendency to ground theory in a set of abstract principles that are only subsequently applied to practical problems makes it easy to ignore (bio)ethically relevant particulars such as the unequal burden borne by women by virtue of their conventional reproductive and nurturing roles, or inequities between social and economic groups. Finally, some feminist theorists are developing alternative methodologies to remedy the epistemological shortcomings of the dominant bioethical model of reasoning.