 The correspondence with Locke, conducted between 1682 and Locke’s taking up residence at Oates, is the largest extant group of letters (some 45 letters survive). Most of Locke’s letters to her have been lost and many of the letters are of a personal nature. But themes include proof of the existence of God and the role of reason in matters of religion. Early on she defends the epistemology of the Cambridge Platonist, John Smith, arguing that there is a supra-rational/elevated form of knowledge accessible by a ‘Higher Principle’ than reason, which may nonetheless be activated with the help of reason. Locke however, dismissed this as a form of ‘Enthusiasm’. Later she commented on the Epitome of Locke’s Essay which he sent her in 1688. 