 To capture the complexity of Diderot’s philosophie as philosophy, this article adopts this reflexive approach. It will proceed in two parts. An overview of Diderot’s life and major texts is offered in Part I so as to present his work and writings as particular episodes in a coherent eighteenth-century life and career. To simplify the reading of this biography, the text is offered in a two-level presentation. A short overview of the highlights of Diderot’s life and work is offered in Section 1 to give readers a schematic overview, but a more extensive presentation of his biography is available in the  Biographical Supplement.  A comprehensive analysis of Diderot’s major philosophical preoccupations as revealed in his writings is then offered in Section 2 so as to outline the contours of Diderot’s place within Enlightenment philosophie and modern philosophy overall. This is followed by brief concluding remarks in Section 3.