 The argument from pragmatic concerns states that whether holist explanations are indispensable is a matter of whether they are pragmatically preferable to individualist explanations. The argument rests on the assumption that whenever a holist explanation of an event is possible, an individualist explanation of that same event is likewise feasible. It is claimed that the choice between these two explanations should be made by appeal to pragmatic considerations. It is maintained, moreover, that it is sometimes preferable from a pragmatic perspective to offer a holist, rather than an individualist explanation. On this basis, it is concluded that holist explanations are indispensable.