 But many things are also different now. For instance, China has emerged as a major player in the genomics field, with the BGI (formerly the Beijing Genomics Institute) already announcing in 2011 the aim to sequence one million genomes. Moreover, DNA sequencing is no longer the only goal of these large-scale initiatives: the new genomics is of course still a genome-based effort, but it is a transformed enterprise that also focuses on data about proteins, DNA  methylation[1]  patterns or the physiology and the environment of the people studied; DNA sequence data now forms only part of a much larger picture in the push for what is called ‘precision’ or ‘personalised’ medicine. Developments such as these have led many to refer to the present as a ‘postgenomic’ age (Richardson &amp; Stevens 2015). The goal of this entry is to look at this constantly developing space of genomic and postgenomic research and outline some of the central philosophical issues it raises.