  The concept of genetic information has a prominent place in the history of molecular genetics, beginning with Watson and Crick's observation that since any sequence of nucleotide base pairs could fit into the structure of any DNA molecule “that in a long molecule many different permutations are possible, and it therefore seems likely that the precise sequence of the bases is the code which carries the genetic information.” (Watson and Crick 1953). As Downes (2005) recounts, the geneticists Jacob and Monod reinforced the use of information language as did those who sought to crack the “genetic code”. By the early 1960s, the language of information was well-entrenched in the field of molecular genetics.