 This is a far-reaching assumption. Penrose’s rationale for invoking state reduction is not that the corresponding randomness offers room for mental causation to become efficacious (although this is not excluded). His conceptual starting point, at length developed in two books (Penrose 1989, 1994), is that elementary conscious acts cannot be described algorithmically, hence cannot be computed. His background in this respect has a lot to do with the nature of creativity, mathematical insight, Gödel’s incompleteness theorems, and the idea of a Platonic reality beyond mind and matter.