 Equation (4) gives the equilibrium frequency of the \(A_2\) allele, under the assumption that it is completely recessive. Note that as \(u\) increases, \(q\)* increases too. This is highly intuitive: the greater the mutation rate from \(A_1\) to \(A_2\), the greater the frequency of \(A_2\) that can be maintained at equilibrium, for a given value of \(s\). Conversely, as \(s\) increases, \(q\)* decreases. This is also intuitive: the stronger the selection against the \(A_2 A_2\) homozygote, the lower the equilibrium frequency of \(A_2\), for a given value of \(u\).