  Beginning with the work of Broca and Wernicke in the 19th century, a  popular view has been that language is localized to certain areas of  the brain (see Fig. 3), almost always the left   hemisphere,[19]  and that it is subject to characteristic patterns of breakdown,  called ‘aphasias.’ (See Saffran 2000 for a survey of the various aphasias.) For example, Broca's area is strongly implicated  in speech production, and damage to this area can result in a  characteristic inability (‘Broca's aphasia’ or  ‘agrammatism’) to produce fluent speech, especially  complex grammatical structures and grammatical morphemes. The fact  that syntax can apparently be selectively interfered with by lesions  to Broca's area has been taken by some to indicate that grammatical  knowledge is localized to that area, and this in turn has been taken  to show support the view that there is a special biological inborn  basis for that knowledge. (Lenneberg 1964, 1967 is the original  proponent of this argument, which is echoed in more recent  discussions, such as Pinker 1994:297-314.)