  Heraclitus (fl. around 500 BC), who repeatedly mentions Pythagoras, attributes wisdom to the soul provided that it is in the right state or condition: “a dry soul”, he claims, “is wisest and best” (fr. 118, KR&amp;S 230). He may have been the first thinker to articulate a connection between soul and motor functions. “A man when he is drunk”, Heraclitus remarks, “is led by an unfledged boy, stumbling and not knowing where he goes, having his soul moist” (fr. 117, KR&amp;S 231). On the most plausible construal of Heraclitus' sentence, he is saying that the drunken person stumbles because his perceptual abilities have been impaired, and this impairment is due to moistness of soul (Schofield 1991, 22). Like many (or indeed all) sixth and fifth century thinkers who expressed views on the nature or constitution of the soul, Heraclitus thought that the soul was bodily, but composed of an unusually fine or rare kind of matter, e.g. air or fire. (A possible exception is the Pythagorean Philolaus, who may have held that the soul is an ‘attunement’ of the body; cf. Barnes 1982, 488-95,  and Huffman.)  The prevalence of the idea that the soul is bodily explains the absence of problems about the relation between soul and body. Soul and body were not thought to be radically different in kind; their difference seemed just to consist in a difference in degree of properties such as fineness and mobility. 