 We too, as rational parts of rational nature, ought to choose in accordance with what will in fact happen (provided we can know what that will be, which we rarely can – we are not gods; outcomes are uncertain to us) since this is wholly good and rational: when we cannot know the outcome, we ought to choose in accordance with what is typically or usually nature’s purpose, as we can see from experience of what usually does happen in the course of nature. In extreme circumstances, however, a choice, for example, to end our lives by suicide can be in agreement with nature. 