 Structural information is effectively based on the transfer of molecular primary sequences (linear sequence) in the synthesis of polypeptides; that is, it is the literal sequence of basic groups (amino acids), before the protein folds into secondary and higher conformations. This is a physical and causal account of information: the new molecule has its sequence because it was templated in some way by the “information”-imparting molecule (in this case, DNA to proteins). Griffiths and Stotz (see below) call this, accordingly, “Crick information”.