 The same inheritance system may be used in multiple inheritance channels. For example, the genetic inheritance system as defined by Jablonka and Lamb is responsible for the inheritance of the information in the DNA in the eukaryotic nucleus and in the DNA of mitochondria. Horizontal gene transfer more generally is considered by Jablonka and Lamb to belong to the genetic system (Jablonka &amp; Lamb 2005:. 233), though it typically involves additional vectors or transmission channels. Conversely, a single inheritance channel may involve multiple inheritance systems, in the sense used by Jablonka and Lamb. For example, DNA methylation, an epigenetic mark, copied in cellular epigentic inheritance, is tied to the copying and transmission of DNA. This arguably constitutes a single channel. Epigenetic mechanisms and heredity play a role in various properties of the genetic system, affecting things such as mutation and recombination rates and hence genetic variation. Perhaps more fundamentally, epigenetic mechanisms are part of the mechanisms ‘operating’ the genetic channel. The inheritance of the genome, when a cell divides, involves recreation of the mother cell’s epigenetic state, a process that goes beyond copying (Lamm 2011, 2014; Lamm &amp; Jablonka 2008).