  Maddy’s first objection to the indispensability argument is that the actual attitudes of working scientists towards the components of well-confirmed theories vary from belief, through tolerance, to outright rejection (Maddy 1992, p. 280). The point is that naturalism counsels us to respect the methods of working scientists, and yet holism is apparently telling us that working scientists ought not have such differential support to the entities in their theories. Maddy suggests that we should side with naturalism and not holism here. Thus we should endorse the attitudes of working scientists who apparently do not believe in all the entities posited by our best theories. We should thus reject  P1.