 It is also important to note that decisional capacity can vary within a single individual over time and in relation to what else is going on. For example, medications can make people drowsy or confused, but between doses when the medication wears off individuals may be perfectly capable of making decisions. Similarly, someone with moderate dementia may become more disoriented in unfamiliar surroundings or in the presence of someone she does not know, and so be less able to focus on a decision. Commitment to maximizing a person’s chance of deciding for herself means that we ought to be sensitive to such factors and should try to assess capacity under the most favorable conditions (Appelbaum 2007).