 Perhaps part of the anti-reductionist consensus in the philosophy of chemistry literature is driven by the stringent demands of Nagel’s account. But even if Nagel’s account is weakened to allow approximative arguments (as Hempel modified his DN model of explanation), as some advocates of reductionism have urged (e.g., Schaffner 1967; Churchland 1985), this still doesn’t circumvent the problem of the appeal to macroscopic properties in the explanation of microscopic properties. Current chemical theory makes essential reference to both microscopic and macroscopic chemical concepts with both chemical and quantum mechanical origins. We know of no convincing substantial examples where either of these aspects have been entirely excised.