  The strong interpretation seeks explanations that cite pathogenic processes in brain systems, just as bodily diseases are explained by processes in other organs. The process at issue need not be destructive, in the sense that it makes the system collapse. Bolton and Hill (2004, 252) note that many mental illnesses seem to be the outcome of systems in a poorly regulated state that is stable, albeit suboptimal. But, as they say, the same is true of hypertension and Cushing’s disease; the idea of a specific pathogenic process in medicine includes dysregulation.