 One of the most interesting ways in which multiple inheritance systems can interact evolutionarily is through processes such as the Baldwin Effect and genetic assimilation. These notions purport to explain how selection can drive developmental responses to environmental demands to become less dependent on the presence of the external stimuli, and become increasingly hereditary (see Ancel 1999, 2000; Crispo 2007; Scheiner 2014, Weber &amp; Depew 2003). In these processes, non-genetic variants affect the selection of genetic variations in favor of those that produce congruent phenotypic results (Jablonka &amp; Lamb 2005/2014: chap. 7). In the simplest case, originally discussed by Baldwin, a developmental response to the environment allows organisms to survive and reproduce for enough generations for genetic mutations to accumulate through natural selection and make the developmental accommodation to the external stimulus unnecessary. The genetic mutations that are favored are those that act in tandem with the developmental response. Conrad Waddington characterized a process he termed genetic assimilation leading to similar results, but emphasized the role played by changes in combinations of genes and reorganization of genetic networks following the reshuffling of genes during the sexual process. The developmentally produced variants that lead the assimilation process need not be hereditary, and may be the result of recurrent plastic developmental responses in each generation. When they are hereditary, however, their inheritance can reinforce their spread in the population.