[usr] I'm so ashamed of myself. I made a big mistake on a project for work. [sys] What did you mess up? [usr] It was something for an important client. Now I'm afraid this is going to screw up my career. [sys] I'm sure you'll be fine.  Have you made many similar mistakes in the past? [usr] No, this is the first time I've messed up anything like this. [qst] [None] [bhv] I'm in a negative mood, please comfort me.
I wouldn't worry too much about it then.  Don't let it get you down.
I made a big mistake on a project for work. Now I'm afraid that it will hurt my career.