/Engine/Plugins/Animation/IKRig/Source/IKRig/Public/Retargeter/IKRetargeter.h
Set the global settings in a retarget profile (will set bApplyGlobalSettings to true).
[UFUNCTION](Programming/UnrealArchitecture/Reference/Functions)(BlueprintCallable, Category=RetargetProfile) static void SetGlobalSettingsInRetargetProfile ( [FRetargetProfile](API\Plugins\IKRig\Retargeter\FRetargetProfile) & RetargetProfile, const [FRetargetGlobalSettings](API\Plugins\IKRig\Retargeter\FRetargetGlobalSettings) & GlobalSettings )